动物营养学报2019，Vol.31Issue(11)：5257-5262,6.DOI:10.3969/j.issn.1006⁃267x.2019.11.042
艾蒿水提物对脂多糖刺激的肉仔鸡小肠黏膜形态的影响
Effects of Artemisia argyi Aqueous Extract on Intestinal Mucosal Morphology of Broilers Stimulated with Lipopolysaccharide
摘要
Abstract
This experiment was conducted to investigate the effects of Artemisia argyi aqueous extract ( AAE) on intestinal mucosal morphology of broilers stimulated with lipopolysaccharide ( LPS). A total of 96 one?day?old AA broilers were randomly divided into 4 treatments ( 6 replicates per treatment, 4 broilers per replicate). Treatments 1 and 2 were fed a basal diet, and treatments 3 and 4 were fed the basal diet supplemented with 1 000 mg／kg AAE. On days 14, 16, 18 and 20, respectively, the broilers in treatments 2 and 4 were intraper?itoneally injected with LPS solution at a dose of 500 μg／kg BW, and the broilers in treatments 1 and 3 were in?jected with the same amount of normal saline. The test period was 21 days. The results showed as follows:when no AAE was added in diets, the villus height of duodenum and jejunum of broilers injected with LPS was significantly lower than that of broilers injected with normal saline ( P＜0.05) , but the addition of AAE to the diet alleviated the decrease of villus height caused by LPS, and there was significant interaction between AAE and LPS ( P＜0.05) ; but for ileum, there were no significant differences in villus height, crypt depth, and the ratio of villus height to crypt depth ( P＞0.05). The above results suggest that AAE can alleviate the intestinal mucosal damage caused by immune stress in broilers stimulated with LPS to a certain extent.[ Chinese Journal of Animal Nutrition, 2019, 31(11) :5256?5261]关键词
艾蒿水提物/肉仔鸡/肠黏膜形态/脂多糖Key words
Artemisia argyi aqueous extract/broiler/intestinal mucosal morphology/lipopolysaccharide分类
农业科技引用本文复制引用
张凌会,杜海东,毛晨羽,张鹏飞,金晓,徐元庆,史彬林..艾蒿水提物对脂多糖刺激的肉仔鸡小肠黏膜形态的影响[J].动物营养学报,2019,31(11):5257-5262,6.基金项目
国家自然科学基金项目(31660674) （31660674）
