国际医药卫生导报2019，Vol.25Issue(24)：3979-3981,3.DOI:10.3760/cma.j.issn.1007-1245.2019.24.001
阳和汤对晚期乳腺癌免疫微环境的影响
Effect of Yanghe decoction on immune microenvironment of advanced breast cancer
摘要
Abstract
Objective Traditional Chinese medicine plays an important role in the treatment of malignant tumors.This articleobserved the effect of Yanghe Decoction on immune-related cells and cancer-induced fatigue in patients with advanced breast cancer.Methods 22 patients with stage Ⅳ breast cancer was confirmed by pathology.The patients received a standard dose of Yanghe decoction,one dose per day,a total of 10 days,21 days as a course of treatment.The interval between two courses of treatment should not exceed two weeks,the patients continued to take the drug to disease progression or intolerable toxic side effects.The treatment period was 4-6 months.Before and after the treatment of Yanghe decoction,the patients were tested for immune micro-environmental indicators,and the patients self-assessed the fatigue status.Result Yanghe decoction significantly increased NK cells and B lymphocytes in patients with advanced breast cancer,and has a significant effect on breast cancer-related fatigue.Conclusion Yanghe decoction improves the tumor immune microenvironment and reduces cancer-induced fatigue,thereby improves the quality of life of cancer patients.关键词
阳和汤/晚期乳腺癌/免疫微环境Key words
Yanghe decoction/Advanced breast cancer/Immune microenvironment引用本文复制引用
李浩,吴依芬,张汉文,叶兆康,樊秀..阳和汤对晚期乳腺癌免疫微环境的影响[J].国际医药卫生导报,2019,25(24):3979-3981,3.基金项目
2018年国家自然科学青年基金(81803877)Youth Program of National Natural Science Foundation of China in 2018(81803877) （81803877）
