中国卒中杂志2019，Vol.14Issue(12)：1205-1208,4.DOI:10.3969/j.issn.1673-5765.2019.12.002
优化溶栓流程对轻型急性缺血性卒中院内延误及预后的影响
Effect of Optimized Thrombolysis Treatment Workflow on In-hospital Delay and Prognosis in Acute Mild Ischemic Stroke
摘要
Abstract
investigate the effect of optimized thrombolysis treatment workflow on door to needle time (DNT) and prognosis in acute mild ischemic stroke patients with intravenous thrombolysis. Methods Data of mild ischemic stroke patients receiving intravenous thrombolysis from July 2015 to June 2017 in the First Qinhuangdao Hospital were retrospectively collected. According to whether thrombolysis treatment workflow was optimized or not, all patients were divided into the optimization group and the control group. Door to needle time (DNT), NIHSS score at 7 days and mRS score at 3 months after thrombolysis of two groups were compared. Results A total of 57 mild ischemic stroke patients were included, with a mean age of 61.7±5.4 years old and 44 males (77.2%). There were 33 patients in optimization group and 24 patients in control group. The general information had no statistical difference between the two groups. DNT was shorter (68.7±19.1 vs 88.8±23.1 min, P=0.001), the percentage of patients with DNT≤60 min was higher (42.4% vs 12.5%, P=0.015), the mRS score at 3 months was lower [0 (0-0.5) vs 0.5 (0-2), P=0.017], and the rate of patients with mRS score≤1 at 3 months was higher (87.9% vs 62.5%, P=0.024) in optimization group, compared with that in control group. Conclusions The optimized thrombolysis treatment workflow can shorten DNT, improve the rate of DNT ≤60 min, and improve 90-day prognosis in patients with acute mild ischemic stroke.关键词
轻型卒中/溶栓流程/院内延误/预后Key words
Mild stroke/Thrombolysis treatment workflow/In-hospital delay/Prognosis引用本文复制引用
王耀辉,张重阳,孙伟,吕喆,刘维斌..优化溶栓流程对轻型急性缺血性卒中院内延误及预后的影响[J].中国卒中杂志,2019,14(12):1205-1208,4.基金项目
河北省重点研发计划项目(172777202) （172777202）
