中国药业2020，Vol.29Issue(2)：21-25,5.DOI:10.3969/j.issn.1006-4931.2020.02.008
某综合医院2013年至2017年多重耐药菌流行病学特点及预防措施
Epidemiological Characteristics and Preventive Measures of Multidrug-Resistant Bacteria in a General Hospital from 2013-2017
摘要
Abstract
Objective to analyze the epidemiological characteristics of multidrug-resistant bacteria In a general hospital from 2013-2017 to provide references for the prevention and treatment of multidrug-resistant bacteria. Methods The positive bacterial culture results of the microbiological lab in the hospital from 2013 to 2017 were selected, and analysis of the composition ratio of the multidrug-resistant bacteria and their relationship with specimen types and the different departments was conducted. Results A total of 9 459 cases of multidrug-resistant bacteria were isolated from 2013-2017. Among them，the top five strains were the carbapenem-resistant Acinetobacter baumannii (CR-AB), carbapenem-resistant Escherichia coli (CR-EC)， carbapenem-resistant Klebsiella pneumonia (CR-KP)，methicillin-resistant staphylococcus aureus (MRSA) and carbapenem-resistant Pseudomonas aeruginosa (CR-PA). The distribution of multidrug-resistant bacteria varied among departments, among which the number of strains isolated in the intensive care unit, departments of respiratory medicine, pediatrics,anorectal and geriatrics was large (2 190,923，676，548 , 519 strains respectively)，and the multidrug-resistant strains in the emergency department and oral surgery were the least isolated (4 strains). Conclusion The hospital's multidrug-resistant bacteria infection has been controlled，but some departments have poor control results, and these departments should pay great attention to it. To implement the scientific and rational use of antibacterial drugs to reduce the occurrence of multidrug-resistant strains，the hospital should strengthen the monitoring of key departments，susceptible populations and high-incidence seasons, strictly control the spread of multidrug-resistant bacteria, and effectively control nosocomial infections, all of which are significant to the prevention and control of the spread of multidrug-resistant bacteria.关键词
多重耐药菌/流行病学/院内感染/合理用药/药房管理Key words
Multidrug-resistant bacteria/epidemiology/nosocomial infection/rational drug use/pharmacy management分类
医药卫生引用本文复制引用
曾强,刘沙,金梅..某综合医院2013年至2017年多重耐药菌流行病学特点及预防措施[J].中国药业,2020,29(2):21-25,5.基金项目
重庆市科卫联合医学科研项目[2018MSXM138]. （）
