IKKβ overexpression together with a lack of tumour suppressor genes causes ameloblastic odontomas in mice
Angustias Page Angel Ramirez Ana Bravo Cristian Suarez-Cabrera Raquel Sanchez-Baltasar Marta Oteo Miguel Angel Morcillo M. Llanos Casanova Jose C. Segovia Manuel Navarro
IKKβ overexpression together with a lack of tumour suppressor genes causes ameloblastic odontomas in mice
IKKβ overexpression together with a lack of tumour suppressor genes causes ameloblastic odontomas in mice
摘要
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Angustias Page,Angel Ramirez,Ana Bravo,Cristian Suarez-Cabrera,Raquel Sanchez-Baltasar,Marta Oteo,Miguel Angel Morcillo,M. Llanos Casanova,Jose C. Segovia,Manuel Navarro..IKKβ overexpression together with a lack of tumour suppressor genes causes ameloblastic odontomas in mice[J].国际口腔科学杂志(英文版),2020,12(1):31-39,9.基金项目
This work was funded by project PI17/00578, from the"Instituto de Salud Carlos Ⅲ"(Ministry of Science, Innovation and Universities) and co-funded by the European Regional Development Fund, and approved by the Ethics Committee of our Institution. It has been founded also by projects CB16/12/00228, PI16/00161, RD16/0011/0011, RD12/0019/0023 and SAF2017-84248-P. We would like to thank Rebeca Sánchez-Domínguez and Omaira Alberquilla for their help with the flow cytometry studies (Ministry of Science, Innovation and Universities)
Federico Sánchez-Sierra and Pilar Hernández for their excellent histological processing of the samples ()
and the personnel of the CIEMAT Animal Unit for mouse care. We also thank Manuel Serrano (Institute for Research in Biomedicine, Barcelona, Spain) for his generous gift of Ink4a/Arf KO mice. Thanks also go to Anton Berns (Netherlands Cancer Institute, NKI, The Netherlands) for supplying the p53EKO mice. (Institute for Research in Biomedicine, Barcelona, Spain)