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IKKβ overexpression together with a lack of tumour suppressor genes causes ameloblastic odontomas in mice

Angustias Page Angel Ramirez Ana Bravo Cristian Suarez-Cabrera Raquel Sanchez-Baltasar Marta Oteo Miguel Angel Morcillo M. Llanos Casanova Jose C. Segovia Manuel Navarro

国际口腔科学杂志(英文版)2020,Vol.12Issue(1):31-39,9.
国际口腔科学杂志(英文版)2020,Vol.12Issue(1):31-39,9.

IKKβ overexpression together with a lack of tumour suppressor genes causes ameloblastic odontomas in mice

IKKβ overexpression together with a lack of tumour suppressor genes causes ameloblastic odontomas in mice

Angustias Page 1Angel Ramirez 2Ana Bravo 3Cristian Suarez-Cabrera 1Raquel Sanchez-Baltasar 2Marta Oteo 3Miguel Angel Morcillo 4M. Llanos Casanova 1Jose C. Segovia 2Manuel Navarro1

作者信息

  • 1. Molecular Oncology Unit. Centro de Investigaciones Energéticas, Medioambientales y Tecnológicas (CIEMAT), Madrid, Spain
  • 2. Instituto de Investigación 12 de Octubre i+12, Madrid, Spain
  • 3. Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain
  • 4. Department of Anatomy, Animal Production and Veterinary Clinical Sciences, Laboratory of Pathology Phenotyping of Genetically Engineered Mice, Faculty of Veterinary Medicine, University of Santiago de Compostela, Lugo, Spain
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摘要

引用本文复制引用

Angustias Page,Angel Ramirez,Ana Bravo,Cristian Suarez-Cabrera,Raquel Sanchez-Baltasar,Marta Oteo,Miguel Angel Morcillo,M. Llanos Casanova,Jose C. Segovia,Manuel Navarro..IKKβ overexpression together with a lack of tumour suppressor genes causes ameloblastic odontomas in mice[J].国际口腔科学杂志(英文版),2020,12(1):31-39,9.

基金项目

This work was funded by project PI17/00578, from the"Instituto de Salud Carlos Ⅲ"(Ministry of Science, Innovation and Universities) and co-funded by the European Regional Development Fund, and approved by the Ethics Committee of our Institution. It has been founded also by projects CB16/12/00228, PI16/00161, RD16/0011/0011, RD12/0019/0023 and SAF2017-84248-P. We would like to thank Rebeca Sánchez-Domínguez and Omaira Alberquilla for their help with the flow cytometry studies (Ministry of Science, Innovation and Universities)

Federico Sánchez-Sierra and Pilar Hernández for their excellent histological processing of the samples ()

and the personnel of the CIEMAT Animal Unit for mouse care. We also thank Manuel Serrano (Institute for Research in Biomedicine, Barcelona, Spain) for his generous gift of Ink4a/Arf KO mice. Thanks also go to Anton Berns (Netherlands Cancer Institute, NKI, The Netherlands) for supplying the p53EKO mice. (Institute for Research in Biomedicine, Barcelona, Spain)

国际口腔科学杂志(英文版)

OACSCDCSTPCDSCI

1674-2818

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