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Comparing different domains of analysis for the characterisation of N-glycans on monoclonal antibodies

Sara Carillo Raquel Pérez-Robles Craig Jakes Meire Ribeiro da Silva Silvia Millán Martín Amy Farrell Natalia Navas Jonathan Bones

药物分析学报（英文）2020，Vol.10Issue(1)：23-34,12.

Comparing different domains of analysis for the characterisation of N-glycans on monoclonal antibodies

Sara Carillo ¹Raquel Pérez-Robles ²Craig Jakes ¹Meire Ribeiro da Silva ³Silvia Millán Martín ¹Amy Farrell ¹Natalia Navas ¹Jonathan Bones²

作者信息

1. Characterisation and Comparability Laboratory, NIBRT-the National Institute for Bioprocessing Research and Training, Foster Avenue, Mount Merrion, Blackrock, Co. Dublin, A94 X099, Ireland
2. Department of Analytical Chemistry, Biohealth Research Institute (ibs.GRANADA), University of Granada, Granada, Spain
3. School of Chemical and Bioprocess Engineering, University College Dublin, Belfield, Dublin 4, D04 V1W8, Ireland
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摘要

关键词

N-Glycans/Biopharmaceuticals/Monoclonal antibodies/Intact mass analysis/Mass spectrometry/Native mass spectrometry/Glycan analysis/Peptide mapping/Glycopeptide analysis

Key words

N-Glycans/Biopharmaceuticals/Monoclonal antibodies/Intact mass analysis/Mass spectrometry/Native mass spectrometry/Glycan analysis/Peptide mapping/Glycopeptide analysis

引用本文复制引用

Sara Carillo,Raquel Pérez-Robles,Craig Jakes,Meire Ribeiro da Silva,Silvia Millán Martín,Amy Farrell,Natalia Navas,Jonathan Bones..Comparing different domains of analysis for the characterisation of N-glycans on monoclonal antibodies[J].药物分析学报（英文）,2020,10(1):23-34,12.

基金项目

The authors gratefully acknowledge funding from Science Foundation Ireland under Grant Number 13/CDA/2196 and collab-orators from Thermo Fisher Scientific for instrument access. （）

药物分析学报（英文）

OASCI

ISSN：2095-1779

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