中国神经再生研究（英文版）2020，Vol.15Issue(10)：1792-1799,8.DOI:10.4103/1673-5374.280300
Green tea catechins inhibit microglial activation which prevents the development of neurological disorders
Tahereh Farkhondeh 1Ali Mohammad Pourbagher-Shahri 2Milad Ashrafizadeh 3Silvia Llorens Folgado 4Ali Rajabpour-Sanati 2Mohammad Reza Khazdair 1Saeed Samarghandian5
作者信息
- 1. Cardiovascular Diseases Research Center, Birjand University of Medical Sciences, Birjand, Iran
- 2. Faculty of Medicine, Birjand University of Medical Sciences, Birjand, Iran
- 3. Department of Basic Science, Faculty of Veterinary Medicine, University of Tabriz, Tabriz, Iran
- 4. Department of Medical Sciences, Faculty of Medicine of Albacete, Centro Regional de Investigaciones Biomédicas (CRIB), University of Castilla-La Mancha, Albacete, Spain
- 5. Healthy Ageing Research Center, Neyshabur University of Medical Sciences, Neyshabur, Iran
- 折叠
摘要
Abstract
The over-activated microglial cells induce neuroinflammation which has the main role in neurological disorders. The over-activated microglia can disturb neuronal function by releasing inflammatory media-tors leading to neuronal dysfunctions and death. Thus, inhibition of over-activated microglia may be an effective therapeutic approach for modulating neuroinflammation. Experimental?studies have indicated ?an-ti-neuroinflammatory?effects of?flavonoids such as green tea catechins. The current research was aimed to review the effect of green tea catechins in inhibiting microglial cells, inflammatory cascades, and subse-quent neurological diseases.关键词
catechins/green tea/microglia/neuroinflammation/neurological diseaseKey words
catechins/green tea/microglia/neuroinflammation/neurological disease引用本文复制引用
Tahereh Farkhondeh,Ali Mohammad Pourbagher-Shahri,Milad Ashrafizadeh,Silvia Llorens Folgado,Ali Rajabpour-Sanati,Mohammad Reza Khazdair,Saeed Samarghandian..Green tea catechins inhibit microglial activation which prevents the development of neurological disorders[J].中国神经再生研究（英文版）,2020,15(10):1792-1799,8.
