国际医药卫生导报2020，Vol.26Issue(4)：484-487,491,5.DOI:10.3760/cma.j.issn.1007-1245.2020.04.013
血清C肽检测在成人隐匿性自身免疫性糖尿病伴NAFLD患者中的临床意义
Clinical significance of serum C-peptide in adult patients with latent autoimmune diabetes mellitus and nonalcoholic fatty liver disease
曲真真 1陈羽 2崔玉良 1赵青1
作者信息
- 1. 德州市人民医院内分泌科 253000
- 2. 德州市人民医院重症监护室 253000
- 折叠
摘要
Abstract
Objective To study the clinical significance of serum C-peptide in adult patients with latent autoimmune diabetes (LADA) and nonalcoholic fatty liver disease (NAFLD).Methods 126 patients with LADA admitted to our hospital from January,2017 to March,2019 were included in the study,and were retrospective analyzed.The incidence of NAFLD in the patients was analyzed.The independent influencing factors of NAFLD in the patients were analyzed by multivariate logistic regression analysis;and the predictive value of serum C-peptide for the LADA patients with NAFLD was judged.Results Of the 126 LADA patients,57.14％(72/126) did not develop NAFLD,while 42.86％ (54/126) did.BMI,total cholesterol,triglyceride,high density lipoprotein cholesterol,low density lipoprotein cholesterol,insulin resistance index,fasting C-peptide,and C-peptide 2 h after meal correlated with the occurrence of NAFLD in the LADA patients (all P＜0.05).Besides total cholesterol,triglyceride,high density lipoprotein cholesterol,low density lipoprotein cholesterol,and insulin resistance index,fasting C-peptide was an independent influencing factors of the LADA patients complicated with NAFLD (P＜ 0.05).Conclusion Serum C-peptide has important clinical significance in predicting LADA complicated with NAFLD.High fasting C-peptide is a risk factor for LADA complicated with NAFLD.关键词
血清C肽/成人隐匿性自身免疫性糖尿病/非酒精性脂肪性肝病Key words
Serum C-Peptide/Latent autoimmune diabetes in adults/Nonalcoholic fatty liver disease引用本文复制引用
曲真真,陈羽,崔玉良,赵青..血清C肽检测在成人隐匿性自身免疫性糖尿病伴NAFLD患者中的临床意义[J].国际医药卫生导报,2020,26(4):484-487,491,5.
