国际眼科杂志2020，Vol.20Issue(2)：191-196,6.DOI:10.3980/j.issn.1672-5123.2020.2.01
自然光照对眼部的影响
Effects of sunlight on the eye
摘要
Abstract
Sunlight consists of lights of continuous spectra. Ultraviolet light and blue light in the sunlight have higher energy. High dose exposure to sunlight can cause direct cellular damage. In the eye, sunlight is known to cause pathological changes in various eye structures. We reviewed the studies on the role of sunlight in corneal diseases, cataracts, glaucoma, and age-related macular degeneration in recent years. Possible sunlight-triggered signaling pathways and mechanisms in the eye are summarized. Excessive exposure to sunlight may lead to increased DNA damage, aberrant protein modification and aggregation, and oxidative stress of ocular tissues, and thus results in the development of ocular diseases. Accordingly, physical protection, topical and/or oral antioxidants and small molecules blocking sunlight -activated signal pathways could be used independently or combinedly to prevent and reduce sunlight - induced ocular damages.关键词
自然光/紫外线/眼部结构/氧化应激/DNA损伤Key words
sunlight/ultraviolet light/ocular structure/oxidative stress/DNA damage引用本文复制引用
刘臻臻,陈少藩,余彤泳,马国书,黄翔宇,余诚莹,林浩添..自然光照对眼部的影响[J].国际眼科杂志,2020,20(2):191-196,6.基金项目
国家自然科学基金(No.81873675) （No.81873675）
国家重点研发计划(No.2018YFC0116500) （No.2018YFC0116500）
中山市科技计划项目—重大专项(No.2016A1003)Foundation items:National Natural Science Foundation (No. 81873675 ) （No.2016A1003）
National Key R&D Program of China (No. 2018YFC0116500 ) （No. 2018YFC0116500 ）
Zhongshan Science and Technology Project (No.2016A1003) （No.2016A1003）
