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首页|期刊导航|中国神经再生研究（英文版）|Human equivalent dose of oral 4-aminopyridine differentiates nerve crush injury from transection injury and improves post-injury function in mice

Human equivalent dose of oral 4-aminopyridine differentiates nerve crush injury from transection injury and improves post-injury function in mice

Chia George Hsu M A Hassan Talukder Li Yue Loel C.Turpin Mark Noble John C.Elfar

中国神经再生研究（英文版）2020，Vol.15Issue(11)：2098-2107,10.
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中国神经再生研究（英文版）2020，Vol.15Issue(11)：2098-2107,10.DOI:10.4103/1673-5374.280319

Human equivalent dose of oral 4-aminopyridine differentiates nerve crush injury from transection injury and improves post-injury function in mice

Human equivalent dose of oral 4-aminopyridine differentiates nerve crush injury from transection injury and improves post-injury function in mice

Chia George Hsu 1M A Hassan Talukder 2Li Yue 3Loel C.Turpin 4Mark Noble 5John C.Elfar2

作者信息

  • 1. Department of Medicine,Aab Cardiovascular Research Institute,University of Rochester School of Medicine and Dentistry,Rochester,NY,USA
  • 2. Center for Orthopaedic Research and Translational Science,Penn State Hershey College of Medicine,Milton S.Hershey Medical Center,Hershey,PA,USA
  • 3. Department of Orthopedics,The Warren Alpert Medical School of Brown University/Rhode Island Hospital,Providence,RI,USA
  • 4. Department of Neuroscience,The University of Rochester Medical Center,Rochester,NY,USA
  • 5. Department of Biomedical Genetics,The University of Rochester Medical Center,Rochester,NY,USA
  • 折叠

摘要

关键词

4-aminopyridine/electron microscopy of nerves/functional recovery/gene expression/muscle force/muscle mass/oral administration/pharmacokinetics/sciatic nerve crush injury/sciatic nerve denervation injury

Key words

4-aminopyridine/electron microscopy of nerves/functional recovery/gene expression/muscle force/muscle mass/oral administration/pharmacokinetics/sciatic nerve crush injury/sciatic nerve denervation injury

分类

医药卫生

引用本文复制引用

Chia George Hsu,M A Hassan Talukder,Li Yue,Loel C.Turpin,Mark Noble,John C.Elfar..Human equivalent dose of oral 4-aminopyridine differentiates nerve crush injury from transection injury and improves post-injury function in mice[J].中国神经再生研究（英文版）,2020,15(11):2098-2107,10.

基金项目

This work was supported by grants from the National Institutes of Health(NIH （）

K08 AR060164-01A)and the Department of Defense(DoD （）

W81XWH-16-1-0725)to JCE in addition to institutional support from the University of Rochester and Pennsylvania State University Medical Centers. （）

中国神经再生研究（英文版）

OACSCDCSTPCDSCI

1673-5374

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