中国组织工程研究2020，Vol.24Issue(30)：4795-4801,7.
血小板计数可作为预测关节假体周围感染的新指标
Platelet count as a novel potential predictor of periprosthetic joint infection
摘要
Abstract
BACKGROUND: Obtaining synovial fluid for diagnostic test of periprosthetic joint infection is invasive and painful to patients. Platelet count is a regular blood test which has been used as a possible predictor of several infectious diseases. Presumably, it could be one of the indicators of periprosthetic joint infection. OBJECTIVE: To identify the accuracies of platelet combined with white blood cell, erythrocyte sedimentation rate or C-reactive protein in the diagnosis of periprosthetic joint infection. METHODS: Patients undergoing revision arthroplasty from March 2013 to December 2018 in the First Affiliated Hospital of Guangzhou University of Chinese Medicine were retrospectively enrolled. A diagnosis of periprosthetic joint infection was confirmed in 77 patients according to the criterions from the Musculoskeletal Infection Society; the remaining 137 patients were confirmed as aseptic cases. White blood cell, erythrocyte sedimentation rate, or C-reactive protein and platelet count were compared between the two groups. The sensitivity, specificity, positive predictive value, and negative predictive value were calculated. RESULTS AND CONCLUSION: The platelet values were significantly increased in periprosthetic joint infection cases. Sensitivity and specificity of the platelet for periprosthetic joint infection were 64.94％ and 86.13％, respectively. Platelet demonstrated a higher accuracy when compared to erythrocyte sedimentation rate and C-reactive protein. In such cases, the platelet shows a certain reference value in confirming the diagnosis of periprosthetic joint infection. Platelet was enough used as adjunct diagnostic tool in patients suspected with periprosthetic joint infection.关键词
关节假体周围感染/无菌性松动/血小板计数/诊断/血小板指数/红细胞沉降率/C-反应蛋白/白细胞计数Key words
periprosthetic joint infection/aseptic loosening/platelet count/diagnosis/platelet indices/erythrocyte sedimentation rate/C-reactive protein/white blood cell count分类
医药卫生引用本文复制引用
曹厚然,谭雪秋,张海涛,曾意荣,邓鹏,叶鹏程,揭珂,曾建春,冯文俊,陈锦伦,齐新宇,李杰..血小板计数可作为预测关节假体周围感染的新指标[J].中国组织工程研究,2020,24(30):4795-4801,7.基金项目
广州中医药大学第一附属医院创新强院工程培育项目(2019IIT35),项目负责人:曾建春the Moral Education Program of Innovation and Strong Academy Project of First Affiliated Hospital of Guangzhou University of Chinese Medicine, No. 2019IIT35 (to ZJC) （2019IIT35）
