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An ultra-sensitive and easy-to-use assay for sensing human UGT1A1 activities in biological systems

Ya-Di Zhu Dan-Dan Wang Guang-Bo Ge Hui-Lin Pang Qi-Hang Zhou Zi-Fei Qin Qiang Jin Moshe Finel Yi-Nan Wang Wei-Wei Qin Yin Lu

药物分析学报(英文)2020,Vol.10Issue(3):263-270,8.
药物分析学报(英文)2020,Vol.10Issue(3):263-270,8.

An ultra-sensitive and easy-to-use assay for sensing human UGT1A1 activities in biological systems

An ultra-sensitive and easy-to-use assay for sensing human UGT1A1 activities in biological systems

Ya-Di Zhu 1Dan-Dan Wang 2Guang-Bo Ge 1Hui-Lin Pang 1Qi-Hang Zhou 2Zi-Fei Qin 3Qiang Jin 1Moshe Finel 4Yi-Nan Wang 1Wei-Wei Qin 5Yin Lu1

作者信息

  • 1. Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China
  • 2. Jiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica, School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, China
  • 3. School of Life Science and Medicine, Dalian University of Technology, Panjin, 124221, China
  • 4. Department of Pharmacy, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China
  • 5. Division of Pharmaceutical Chemistry and Technology, Faculty of Pharmacy, University of Helsinki, 00014, Finland
  • 折叠

摘要

关键词

UGT1A1/LC-FD/N-butyl-4-(4-hydroxyphenyl)-1/8-/naphthalimide/Modulators

Key words

UGT1A1/LC-FD/N-butyl-4-(4-hydroxyphenyl)-1/8-/naphthalimide/Modulators

引用本文复制引用

Ya-Di Zhu,Dan-Dan Wang,Guang-Bo Ge,Hui-Lin Pang,Qi-Hang Zhou,Zi-Fei Qin,Qiang Jin,Moshe Finel,Yi-Nan Wang,Wei-Wei Qin,Yin Lu..An ultra-sensitive and easy-to-use assay for sensing human UGT1A1 activities in biological systems[J].药物分析学报(英文),2020,10(3):263-270,8.

基金项目

This work was finically supported by the NSF of China (81773687, 81922070, 81973286, 81703604), the National Key Research and Development Program of China (2017YFC1700200, 2017YFC1702000), the Open Project Program of Jiangsu Key Labo-ratory for Pharmacology and Safety Evaluation of Chinese Materia Medica (No.JKLPSE-201803), the Project of the Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD), Program of Shanghai Academic/Technology Research Leader (18XD1403600), Drug Innovation Major Project (2018ZX09731016), Shuguang Program (18SG40) supported by Shanghai Education Development Foundation and Shanghai Municipal Education Commission, and the Graduate Innovation Project of Shanghai University of Traditional Chinese Medicine (Y2019063). (81773687, 81922070, 81973286, 81703604)

药物分析学报(英文)

OASCI

2095-1779

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