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Ionomycin ameliorates hypophosphatasia via rescuing alkaline phosphatase deficiency-mediated L-type Ca2+channel internalization in mesenchymal stem cells

Bei Li Yimin Zhao Songtao Shi Yan Jin Xiaoning He Zhiwei Dong Kun Xuan Wei Sun Li Gao Shiyu Liu Wenjia Liu Chenghu Hu

骨研究（英文版）2020，Vol.8Issue(2)：182-196,15.

Ionomycin ameliorates hypophosphatasia via rescuing alkaline phosphatase deficiency-mediated L-type Ca2+channel internalization in mesenchymal stem cells

Bei Li ¹Yimin Zhao ²Songtao Shi ¹Yan Jin ³Xiaoning He ⁴Zhiwei Dong ¹Kun Xuan ²Wei Sun ¹Li Gao ²Shiyu Liu ¹Wenjia Liu ⁵Chenghu Hu⁶

作者信息

1. State Key Laboratory of Military Stomatology&National Clinical Research Center for Oral Diseases&Shaanxi International Joint Research Center for Oral Diseases,Center for Tissue Engineering,School of Stomatology,The Fourth Military Medical University,Xi’an 710032 Shaanxi,China
2. Xi’an Institute of Tissue Engineering and Regenerative Medicine,Xi’an,China
3. Department of Anatomy and Cell Biology,University of Pennsylvania School of Dental Medicine,Philadelphia,PA,USA
4. South China Center of Craniofacial Stem Cell Research,Guanghua School of Stomatology,Sun Yat-sen University,74 Zhongshan 2Rd,Guangzhou,Guangdong,China
5. Department of Pediatric Dentistry,School of Stomatology,Fourth Military Medical University,Xi’an,China
6. Institute for Biomedical Sciences of Pain,Tangdu Hospital,Fourth Military Medical University,Xi’an,China
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摘要

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Bei Li,Yimin Zhao,Songtao Shi,Yan Jin,Xiaoning He,Zhiwei Dong,Kun Xuan,Wei Sun,Li Gao,Shiyu Liu,Wenjia Liu,Chenghu Hu..Ionomycin ameliorates hypophosphatasia via rescuing alkaline phosphatase deficiency-mediated L-type Ca2+channel internalization in mesenchymal stem cells[J].骨研究（英文版）,2020,8(2):182-196,15.

基金项目

This study was funded by grants from the National Natural Science Foundation of China (Nos.81620108007 and 81870768),the National Key Research and Develop-ment Program of China (Nos.2016YFC1101400 and 2017YFA0104800),the Scientific Young Alma of Shaanxi province (2018KJXX-015) and a Schoenleber pilot grant from the University of Pennsylvania School of Dental Medicine. （Nos.81620108007 and 81870768）

骨研究（英文版）

OACSCDSCI

ISSN：2095-4700

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