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The therapeutic potential of targeting exchange protein directly activated by cyclic adenosine 3′,5′-monophosphate (Epac) for central nervous system trauma

Alba Guijarro-Belmar Dominik Mateusz Domanski Xuenong Bo Derryck Shewan Wenlong Huang

中国神经再生研究（英文版）2021，Vol.16Issue(3)：460-469,10.

The therapeutic potential of targeting exchange protein directly activated by cyclic adenosine 3′,5′-monophosphate (Epac) for central nervous system trauma

Alba Guijarro-Belmar ¹Dominik Mateusz Domanski ²Xuenong Bo ¹Derryck Shewan ³Wenlong Huang¹

作者信息

1. Institute of Medical Sciences, School of Medicine, Medical Sciences & Nutrition, University of Aberdeen, Aberdeen, UK
2. Sainsbury Wellcome Centre, University College London, London, UK
3. Center for Neuroscience, Surgery and Trauma, Queen Mary University of London, London, UK
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摘要

关键词

astrocytes/axonal regeneration/cAMP/central nervous system regeneration/Epac/glial scar/microglia/neuroinflammation/neurons/spinal cord/spinal cord injury/traumatic spinal cord injury

Key words

引用本文复制引用

Alba Guijarro-Belmar,Dominik Mateusz Domanski,Xuenong Bo,Derryck Shewan,Wenlong Huang..The therapeutic potential of targeting exchange protein directly activated by cyclic adenosine 3′,5′-monophosphate (Epac) for central nervous system trauma[J].中国神经再生研究（英文版）,2021,16(3):460-469,10.

基金项目

This work was supported by Scottish Rugby Union funding to WH and DS, the NRB PhD scholarship from the International Spinal Rsesarch Trust to AGB, and a Hot-Start Scholarship from the University of Aberdeen to DD. （）

中国神经再生研究（英文版）

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ISSN：1673-5374

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