数字中医药（英文）2020，Vol.3Issue(3)：188-198,11.DOI:10.1016/j.dcmed.2020.09.005
火索麻叶提取物的抗氧化、抗菌和促愈作用探索
Antioxidant, Antimicrobial and Wound Healing Potential of Helicteres isora Linn. Leaf Extracts
摘要
Abstract
Objective To investigate the antioxidant, antimicrobial and wound healing potential of Helicteres isora Linn. leaf extracts. Methods The petroleum ether, chloroform, acetone, ethanol and hydroalcoholic extracts of leaves were screened for phytochemicals. The 1,1-diphenyl-2-picrylhydrazyl (DPPH), nitric oxide (NO) radical scavenging tests and reducing power assays were performed to measure antioxidant activity; disc diffusion methods were used to evaluate antimicrobial potential. Wound healing activity was evaluated by incision and excision wound rat models. Results The extracts contained mainly sterols and flavonoids. The hydroalcoholic extract showed remarkable antioxidant and antimicrobial potential and significant (P < 0.05) wound healing activity. Conclusions The identified activities of the hydroalcoholic extract may be attributable to its constituent phytochemicals.关键词
火索麻/植物化学成分筛选/抗氧化/抗菌/切口/切痂/上皮化时期Key words
Helicteres isora Linn/Phytochemical screening/Antioxidant/Antimicrobial/Incision wound/Excision wound/Period of epithelization引用本文复制引用
RENUKA Mahajan,PRAKASH Itankar..火索麻叶提取物的抗氧化、抗菌和促愈作用探索[J].数字中医药（英文）,2020,3(3):188-198,11.基金项目
The authors would like to acknowledge Department of Pharmaceutical Sciences, Rashtrasant Tukadoji Maharaj Nagpur University Nagpur for the provision of the necessary facilities to perform the study. （）
