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TOSO interacts with SYK and enhances BCR pathway activation in chronic lymphocytic leukemia

Yan-Ru Zhang Shu-Hua Yi Zhen Yu Wen-Jie Xiong Xu-Xiang Liu Hui-Min Liu Rui Cui Qi Wang Wen-Ming Chen Lu-Gui Qiu

中华医学杂志(英文版)2020,Vol.133Issue(17):2090-2097,8.
中华医学杂志(英文版)2020,Vol.133Issue(17):2090-2097,8.DOI:10.1097/CM9.0000000000000999

TOSO interacts with SYK and enhances BCR pathway activation in chronic lymphocytic leukemia

TOSO interacts with SYK and enhances BCR pathway activation in chronic lymphocytic leukemia

Yan-Ru Zhang 1Shu-Hua Yi 2Zhen Yu 1Wen-Jie Xiong 1Xu-Xiang Liu 1Hui-Min Liu 3Rui Cui 1Qi Wang 1Wen-Ming Chen 4Lu-Gui Qiu1

作者信息

  • 1. State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin 300020, China
  • 2. Department of Hematology, Beijing Chao Yang Hospital Affiliated to Capital Medical University, Beijing 100043, China
  • 3. Department of Pathology, City of Hope National Medical Center, Duarte 91010, CA, USA
  • 4. Department of Hematology, Tianjin First Center Hospital, Tianjin 300192, China
  • 折叠

摘要

关键词

Chronic lymphocytic leukemia/TOSO/B-cell receptor signaling pathway/SYK/Apoptosis

Key words

Chronic lymphocytic leukemia/TOSO/B-cell receptor signaling pathway/SYK/Apoptosis

引用本文复制引用

Yan-Ru Zhang,Shu-Hua Yi,Zhen Yu,Wen-Jie Xiong,Xu-Xiang Liu,Hui-Min Liu,Rui Cui,Qi Wang,Wen-Ming Chen,Lu-Gui Qiu..TOSO interacts with SYK and enhances BCR pathway activation in chronic lymphocytic leukemia[J].中华医学杂志(英文版),2020,133(17):2090-2097,8.

基金项目

This work was supported by grants from the National Nature Science Foundation of China (Nos.81200395 and 81970187),Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences grants (No.2017-I2M-3-018),and Fundamental Application and Advanced and Technology Research Program of Tianjin (No.15JCYBJC25100). (Nos.81200395 and 81970187)

中华医学杂志(英文版)

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