The Mechanisms of Pei-yuan-Tong-nao Capsule as a Therapeutic Agent against Cerebrovascular DiseaseOACSTPCD
The Mechanisms of Pei?yuan?Tong?nao Capsule as a Therapeutic Agent against Cerebrovascular Disease
Objective: Pei?Yuan?Tong?Nao (PYTN) capsule has been widely used for the treatment of cerebrovascular disease (CVD), including cerebral ischemia. However, due to the complexity of traditional Chinese Medicine (TCM) and the lack of proper inspection methods, the pharmacological mechanisms of the actions of PYTN capsule on CVD remain ambiguous. In this investigation, a network pharmacology method was used to investigate the mechanism of action of PYTN capsule …查看全部>>
Yu Wei;Xiao‑Jing Fan;Ming‑Hui Zhang;Mai‑Qiu Wu;Wei Li;Ping Wang;Wei Xiong;Jian‑Ping Lin
State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai UniversityDepartment of Cerebral Acupuncture, The Second Affiliated Hospital of Tianjin University of Traditional Chinese MedicinePlatform of Pharmaceutical Intelligence, Tianjin International Joint Academy of BiomedicineState Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai UniversityBiodesign Center, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, TianjinState Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai UniversityBiodesign Center, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, TianjinDepartment of Neurology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing
Cerebrovascular diseasemechanismnetwork pharmacologyPei‑Yuan‑Tong‑Naotraditional Chinese medicine
Cerebrovascular diseasemechanismnetwork pharmacologyPei‑Yuan‑Tong‑Naotraditional Chinese medicine
《世界中医药杂志(英文版)》 2020 (3)
331-340,10
This study was supported by the National Key R and D Program of China?(No.2017YFC1104400).
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