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从非酒精性脂肪性肝病到代谢性脂肪性肝病——基于疾病异质性角度的分析

冯巩 严琴琴 贺娜 弥曼

临床肝胆病杂志2020,Vol.36Issue(11):2597-2600,4.
临床肝胆病杂志2020,Vol.36Issue(11):2597-2600,4.DOI:10.3969/j.issn.1001-5256.2020.11.045

从非酒精性脂肪性肝病到代谢性脂肪性肝病——基于疾病异质性角度的分析

From nonalcoholic fatty liver disease to metabolic fatty liver disease:An analysis based on disease heterogeneity

冯巩 1严琴琴 1贺娜 2弥曼1

作者信息

  • 1. 西安医学院全科医学研究所,西安 710021
  • 2. 西安医院第一附属医院 消化内科,西安 710021
  • 折叠

摘要

Abstract

Nonalcoholic fatty liver disease (NAFLD) has become the most important chronic liver disease in the world, but there is still no approved drug for clinical practice. Due to the heterogeneity of NAFLD Itself, although drug therapy is being developed, the response rate seems to remain low. In order to meet the needs of clinical trial design and provide accurate information for drug developers,relevant sholars have proposed to change the name of NAFLD to metabolic associated fatty liver disease This article summarizes the origin of NAFLD heterogeneity and the background of NAFLD renaming, so as to provide new ideas for accelerating the development of new therapies.

关键词

非酒精性脂肪性肝病/代谢性脂肪性肝病/异质性

Key words

non-alcoholic/fatty liver disease/metabolic fatty liver disease/heterogeneity

分类

医药卫生

引用本文复制引用

冯巩,严琴琴,贺娜,弥曼..从非酒精性脂肪性肝病到代谢性脂肪性肝病——基于疾病异质性角度的分析[J].临床肝胆病杂志,2020,36(11):2597-2600,4.

基金项目

2020陕西省高等教育学会"疫情防控专项研究课题"(XGH20043) (XGH20043)

临床肝胆病杂志

OA北大核心CSTPCD

1001-5256

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