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Neuroprotective and anti-inflammatory effects of a therapy combining agonists of nicotinic α7 and σ1 receptors in a rat model of Parkinson's disease

Steven Vetel Laura Foucault-Fruchard Claire Tronel Frédéric Buron Jackie Vergote Sylvie Bodard Sylvain Routier Sophie Sérrière Sylvie Chalon

中国神经再生研究（英文版）2021，Vol.16Issue(6)：1099-1104,6.

Neuroprotective and anti-inflammatory effects of a therapy combining agonists of nicotinic α7 and σ1 receptors in a rat model of Parkinson's disease

Steven Vetel ¹Laura Foucault-Fruchard ¹Claire Tronel ²Frédéric Buron ¹Jackie Vergote ³Sylvie Bodard ¹Sylvain Routier ¹Sophie Sérrière ³Sylvie Chalon¹

作者信息

1. UMR 1253, iBrain, Université de Tours, Inserm, Tours, France
2. CHU Tours, Service pharmacie, Tours, France
3. Institut de Chimie Organique et Analytique, ICOA, UMR CNRS 7311, Université d'Orléans, Orléans, France
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摘要

关键词

6-hydroxydopamine/astrocytes/microglial activation/neurodegeneration/neuroinflammation/nicotinic α7 receptor/Parkinson's disease/PHA 543613/PRE-084/sigma-1 receptor

Key words

6-hydroxydopamine/astrocytes/microglial activation/neurodegeneration/neuroinflammation/nicotinic α7 receptor/Parkinson's disease/PHA 543613/PRE-084/sigma-1 receptor

分类

医药卫生

引用本文复制引用

Steven Vetel,Laura Foucault-Fruchard,Claire Tronel,Frédéric Buron,Jackie Vergote,Sylvie Bodard,Sylvain Routier,Sophie Sérrière,Sylvie Chalon..Neuroprotective and anti-inflammatory effects of a therapy combining agonists of nicotinic α7 and σ1 receptors in a rat model of Parkinson's disease[J].中国神经再生研究（英文版）,2021,16(6):1099-1104,6.

基金项目

This work was supported by Inserm(to SV,LFF,CT,JV,SB,SS,SC)and by the Labex IRON(ANR-11-LABX-18-01:to all authors). （to SV,LFF,CT,JV,SB,SS,SC）

中国神经再生研究（英文版）

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ISSN：1673-5374

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