国际眼科杂志2021，Vol.21Issue(1)：1-8,8.DOI:10.3980/j.issn.1672-5123.2021.1.01
圆锥角膜快速跨上皮交联手术前后Corvis ST参数的重复性及差异性
Repeatability and comparison of Corvis ST parameters before and after accelerated transepithelial corneal cross-linking in keratoconus eyes
摘要
Abstract
?AIM:To evaluate the repeatability and comparison of corneal visualization scheimpflug technology ( Corvis ST) parameters in keratoconus eyes before and after accelerated transepithelial corneal cross-linking ( ATE-CXL) .?METHODS:Thirty eyes of 30 progressive keratoconus patients were included in the prospective study. Three repeated corneal biomechanical measurements were performed preoperatively and one month postoperatively by Corvis ST. The interclass correlation coefficient ( ICC) and 95％ confidence interval ( CI ) , Cronbach ' α, repeatability coefficient ( RC) , and coefficient of variation ( CV) were used to evaluate the repeatability of Corvis ST parameters. Paired t-test or Wilcoxon rank test was used to evaluate the differences between preoperative and postoperative data.? RESULTS:At preoperative, 26 of 39 ( 66. 67％) parameters showed good to excellent repeatability, 6 ( 15.38％) showed moderate, and 7 ( 17. 95％) showed poor repeatability. Similarly, 34 ( 87. 18％) parameters showed good to excellent repeatability, 3 ( 7.69％) showed moderate, and 2 ( 5.13％) showed poor repeatability after ATE-CXL. After ATE-CXL 1mo, the intraocular pressure ( IOP ) , biomechanical corrected IOP ( bIOP ) , first applanation time (A1T), Radius, deformation amplitude at the first applanation (A1DA), deflection length at the maximum deformation ( HCDLL ) and stiffness parameter at first applanation ( SP A1) parameters increased, while the steep keratometry ( Ks) , flat keratometry ( Kf) , mean keratometry ( Kmean ) , second applanation time ( A2T ) , DA Ratio Max ( 2 mm) and integrated radius parameters decreased ( all P<0.05) .? CONCLUSION:The repeatability of the Corvis ST parameters before and 1mo ATE-CXL follow up were both acceptable, and the corneal stiffness was improved after 1mo ATE-CXL.关键词
圆锥角膜/快速跨上皮交联/Corvis ST参数/可重复性/早期角膜生物力学改变Key words
keratoconus/accelerated transepithelial corneal cross-linking/Corvis ST parameters/repeatability/early corneal biomechanical changes引用本文复制引用
杨凯丽,顾宇伟,范棋,徐丽妍,庞辰久,任胜卫..圆锥角膜快速跨上皮交联手术前后Corvis ST参数的重复性及差异性[J].国际眼科杂志,2021,21(1):1-8,8.基金项目
河南省自然科学基金项目(No.182300410362) （No.182300410362）
山东省眼科学重点实验室开放课题自主项目(No.2018-04)Natural Science Foundation of Henan Province(No.182300410362) （No.2018-04）
Shandong Key Laboratory of Ophthalmology Open Subject Independent Project(No.2018-04) （No.2018-04）
