Interaction mechanism of egg white-derived ACE inhibitory peptide TNGIIR with ACE and its effect on the expression of ACE and AT1 receptorOA
The egg white-derived hexapeptide TNGIIR inhibits angiotensin-converting enzyme(ACE)activity in vitro.In this work,molecular docking revealed that TNGIIR established hydrogen bonds with the S1(Ala 354),S2(Gln 281,His 513,Tyr …查看全部>>
Zhipeng Yu;Hui Guo;David Shiuan;Chensi Xia;Wenzhu Zhao;Long Ding;Fuping Zheng;Jingbo Liu
College of Food Science and Engineering,Bohai University,Jinzhou 121013,PR China Beijing Advanced Innovation Center for Food Nutrition and Human Health,Beijing Technology and Business University(BTBU),Beijing 102488,PR ChinaCollege of Food Science and Engineering,Bohai University,Jinzhou 121013,PR ChinaCollege of Food Science and Engineering,Bohai University,Jinzhou 121013,PR ChinaCollege of Food Science and Engineering,Bohai University,Jinzhou 121013,PR ChinaCollege of Food Science and Engineering,Bohai University,Jinzhou 121013,PR ChinaLab of Nutrition and Functional Food,Jilin University,Changchun 130062,PR ChinaBeijing Advanced Innovation Center for Food Nutrition and Human Health,Beijing Technology and Business University(BTBU),Beijing 102488,PR ChinaLab of Nutrition and Functional Food,Jilin University,Changchun 130062,PR China
化学工程
Egg white proteinsACE inhibitory peptideGene expressionAntihypertensive effectMolecular docking
《食品科学与人类健康(英文)》 2020 (1)
P.52-57,6
the National Natural Science Funds of China(No.31901635)Beijing Advanced Innovation Centre for Food Nutrition and Human Health(Grant No.20181036).
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