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A novel negative regulatory mechanism of Smurf2 in BMP/Smad signaling in bone

Junichi Kushioka Jeffrey L.Wrana Yasumichi Inoue Hiroko Ninomiya Shin Yamamoto Takashi Saitou Hideki Yoshikawa Takeshi Imamura Takashi Kaito Rintaro Okada Hiroyuki Ishiguro Zeynep Bal Joe Kodama Ryota Chijimatsu Melanie Pye Masahiro Narimatsu

骨研究（英文版）2020，Vol.8Issue(4)：429-438,10.

A novel negative regulatory mechanism of Smurf2 in BMP/Smad signaling in bone

Junichi Kushioka ¹Jeffrey L.Wrana ²Yasumichi Inoue ³Hiroko Ninomiya ⁴Shin Yamamoto ⁵Takashi Saitou ⁴Hideki Yoshikawa ⁶Takeshi Imamura ¹Takashi Kaito ⁴Rintaro Okada ⁶Hiroyuki Ishiguro ¹Zeynep Bal ¹Joe Kodama ¹Ryota Chijimatsu ¹Melanie Pye ¹Masahiro Narimatsu⁷

作者信息

1. Department of Orthopaedic Surgery,Osaka University Graduate School of Medicine,2-2 Yamadaoka,Suita,Osaka 565-0871,Japan
2. Centre for Systems Biology,Lunenfeld-Tanenbaum Research Institute,Mount Sinai Hospital,600 University Ave,Toronto,ON M5G 1X5,Canada
3. Department of Cell Signaling,Graduate School of Pharmaceutical Sciences,Nagoya City University,3-1 Tanabe-dori,Mizuho-ku,Nagoya,Aichi 467-8603,Japan
4. Department of Molecular Medicine for Pathogenesis,Ehime University Graduate School of Medicine,454 Shitsukawa,Toon,Ehime 791-0295,Japan
5. Department of Gastroenterology and Metabology,Ehime University Graduate School of Medicine,454 Shitsukawa,Toon,Ehime 791-0295,Japan
6. Translational Research Center,Ehime University Hospital,454 Shitsukawa,Toon,Ehime 791-0295,Japan
7. Bone and Cartilage Regenerative Medicine,The University of Tokyo,7-3-1,Hongo,Bunkyo-ku,Tokyo 113-8655,Japan
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摘要

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Junichi Kushioka,Jeffrey L.Wrana,Yasumichi Inoue,Hiroko Ninomiya,Shin Yamamoto,Takashi Saitou,Hideki Yoshikawa,Takeshi Imamura,Takashi Kaito,Rintaro Okada,Hiroyuki Ishiguro,Zeynep Bal,Joe Kodama,Ryota Chijimatsu,Melanie Pye,Masahiro Narimatsu..A novel negative regulatory mechanism of Smurf2 in BMP/Smad signaling in bone[J].骨研究（英文版）,2020,8(4):429-438,10.

基金项目

This work was supported by the JSPS Grant-in-Aid (C) grant number 17K11005 and the JSPS bilateral Joint Research Project grant number 1007397 to T.K., MEXT/JSPS grant number JP19K12218 to T.S., MEXT/JSPS grant number JP15H05952 ("Resonance Bio") to T.S. and T.I., and MEXT/JSPS KAKENHI grant number JP16H06280 ("Advanced Bioimaging Support") to T.I. The sponsors of this study were not directly involved in its development or execution. The authors would like to thank Ms. Fumiko Hirayama, Ms. Yukiko Eguchi, and Ms. Mari Shinkawa for their exceptional contribution to this work. （C）

骨研究（英文版）

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ISSN：2095-4700

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