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Evading the host response:Staphylococcus"hiding"in cortical bone canalicular system causes increased bacterial burden

Stephen D.Zoller Daniel O.Johansen Ryan A.Smith Marina M.Sprague Kellyn R.Hori Samuel J.Clarkson Rachel Borthwell Scott I.Simon Jeff F.Miller Scott D.Nelson Nicholas M.Bernthal Vishal Hegde Zachary D.C.Burke Howard Y.Park Chad R.Ishmael Gideon W.Blumstein William Sheppard Christopher Hamad Amanda H.Loftin

骨研究（英文版）2020，Vol.8Issue(4)：447-457,11.

Evading the host response:Staphylococcus"hiding"in cortical bone canalicular system causes increased bacterial burden

Stephen D.Zoller ¹Daniel O.Johansen ¹Ryan A.Smith ²Marina M.Sprague ³Kellyn R.Hori ¹Samuel J.Clarkson ²Rachel Borthwell ²Scott I.Simon ²Jeff F.Miller ⁴Scott D.Nelson ⁵Nicholas M.Bernthal ⁶Vishal Hegde ⁷Zachary D.C.Burke ¹Howard Y.Park ¹Chad R.Ishmael ¹Gideon W.Blumstein ¹William Sheppard ¹Christopher Hamad ¹Amanda H.Loftin¹

作者信息

1. Department of Orthopedic Surgery,University of California,Los Angeles,1250 16th St Suite 2100,Santa Monica,CA 90404,USA
2. David Geffen School of Medicine,University of California,Los Angeles,10833 Le Conte Ave,Los Angeles,CA 90095,USA
3. Department of Internal Medicine,University of California,Los Angeles,757 Westwood Plaza,Suite 7501,Los Angeles,CA 90095,USA
4. Department of Biomedical Engineering,University of California,Davis,Davis,CA 95616,USA
5. California Nano Systems Institute,University of California,Los Angeles,570 Westwood Plaza,Los Angeles,CA 90095,USA
6. Department of Microbiology,Immunology,and Molecular Genetics,David Geffen School of Medicine,University of California,Los Angeles 90095,USA
7. Department of Pathology,University of California,Los Angeles,1250 16th St Suite 3450,Santa Monica,CA 90404,USA
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Stephen D.Zoller,Daniel O.Johansen,Ryan A.Smith,Marina M.Sprague,Kellyn R.Hori,Samuel J.Clarkson,Rachel Borthwell,Scott I.Simon,Jeff F.Miller,Scott D.Nelson,Nicholas M.Bernthal,Vishal Hegde,Zachary D.C.Burke,Howard Y.Park,Chad R.Ishmael,Gideon W.Blumstein,William Sheppard,Christopher Hamad,Amanda H.Loftin..Evading the host response:Staphylococcus"hiding"in cortical bone canalicular system causes increased bacterial burden[J].骨研究（英文版）,2020,8(4):447-457,11.

基金项目

Research reported in this publication was supported by the Musculoskeletal Transplant Foundation/Musculoskeletal Tumor Society grant number 20161236. Research reported in this publication was supported by the National Institute of Arthritis and Musculoskeletal and Skin Diseases of the National Institutes of Health under the Ruth L. Kirschstein National Research Service Award Number T32AR059033 and Award Number 5K08AR069112-01. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. Confocal laser scanning microscopy was performed at the CNSI Advanced Light Microscopy/Spectroscopy Shared Resource Facility at UCLA, supported with funding from NIH-NCRR shared resources grant (CJX1-443835-WS-29646) and NSF Major Research Instrumentation grant (CHE-0722519). Support for LysEGFP mice was provided by the Training Program in Pharmacology: From Bench to Bedside at the University of California, Davis, supported by Grant NIH T32 GM099608 (to Leif S. Anderson). Statistical support was provided by Nicholas J. Jackson, Ph.D. MPH, and the research described was supported by NIH/National Center for Advancing Translational Science (NCATS) UCLA CTSI Grant Number UL1TR001881. The authors thank Leif Anderson, Ph.D., for his assistance in providing LysEGFP mice to our lab. The authors thank John S. Adams M.D. for critical input on methodology and results. （CJX1-443835-WS-29646）

骨研究（英文版）

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ISSN：2095-4700

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