数字中医药（英文）2021，Vol.4Issue(1)：64-70,7.DOI:10.1016/j.dcmed.2021.03.005
症状性颈动脉重度狭窄/闭塞患者证候要素与前交通动脉开放的关系
Relationship between syndrome elements and anterior communi-cating artery opening in patients with smptomatic severe carotid artery stenosis/occlusion
摘要
Abstract
Objective To study the relationship between syndrome elements and anterior communicating artery (ACoA) opening in patients with symptomatic severe carotid artery stenosis/occlusion. Methods Thirty-six patients with symptomatic severe carotid stenosis/occlusion were collected, including 26 patients with cerebral infarction and 10 patients with transient ischemic attack (TIA). Syndrome elements at five time points were collected. Computer tomography angiography (CTA) combined with magenic resonance angiograp (MRA) was used to evaluate the primary collateral circulation, and the prognosis and syndrome elements were statistically analyzed according to whether the ACoA was open or not. Results The ACoA was open more in the primary collateral circulation among patients with symptomatic severe carotid stenosis/occlusion. There was a statistically significant difference in national institute of health stroke scale (NIHSS) score improvement and good prognosis [the modified rankin scale (mRS) ≤ 2] between the ACoA open group and the ACoA non-open group on the 90th day (P < 0.05). The proportion of patients with internal wind syndrome, blood stasis syndrome, Qi deficiency syndrome, and Yin deficiency syndrome in the ACoA non-open group was higher than that in the open group. Conclusion In the patients with severe carotid artery stenosis/occlusion, the group with presence of anterior communicating artery had better prognosis. The syndrome elements are more complex in the group without the presence of anterior communicating artery. The proportion of Qi deficiency syndrome was positively correlated with the non-opening of anterior communicating artery. The imaging evaluation of collateral circulation can provide guidance for syndrome differentiation and treatment.关键词
颈动脉狭窄/前交通动脉/侧支循环/证候要素/虚证Key words
Carotid artery stenosis/Anterior communicating artery (ACoA)/Collateral circulation/Syndrome elements/Deficiency syndrome引用本文复制引用
甄飞,孟繁兴,窦金娟,Louis Lei Jin,邱继文..症状性颈动脉重度狭窄/闭塞患者证候要素与前交通动脉开放的关系[J].数字中医药（英文）,2021,4(1):64-70,7.基金项目
We thank for the funding support from the Science &Technology Development Fund of Tianjin Education Commission for Higher Education (No. 2017KJ150). （No. 2017KJ150）
