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Study of intracellular anabolism of 5-fluorouracil and incorporation in nucleic acids based on an LC-HRMS method

Christelle Machon Jérôme Guitton Frédéric Catez Nicole Dalla Venezia Floriane Vanhalle Laetitia Guyot Anne Vincent Maxime Garcia Béatrice Roy Jean-Jacques Diaz

药物分析学报（英文）2021，Vol.11Issue(1)：77-87,11.

Study of intracellular anabolism of 5-fluorouracil and incorporation in nucleic acids based on an LC-HRMS method

Christelle Machon ¹Jérôme Guitton ²Frédéric Catez ³Nicole Dalla Venezia ²Floriane Vanhalle ³Laetitia Guyot ⁴Anne Vincent ³Maxime Garcia ³Béatrice Roy ²Jean-Jacques Diaz²

作者信息

1. Laboratoire de Chimie Analytique, Faculté de Pharmacie de Lyon, Université Lyon 1, 8 Avenue Rockefeller, Lyon, 69373, France
2. Laboratoire de Biochimie et de Pharmaco-toxicologie, Centre Hospitalier Lyon -Sud-HCL, Pierre Benite, 69495, France
3. Inserm U1052, CNRS UMR5286 Centre de Recherche en Cancérologie de Lyon, F-69000 Lyon, France. Centre Léon Bérard, F-69008 Lyon, France, Universitéde Lyon 1, F-69000 Lyon, France
4. Laboratoire de toxicologie, Faculté de pharmacie de Lyon, 8 avenue Rockefeller, F-69373 Lyon, France
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摘要

关键词

5-Fluorouracil/LC-MS-HRMS/Nucleotide/RNA/DNA/Incorporation rate

Key words

5-Fluorouracil/LC-MS-HRMS/Nucleotide/RNA/DNA/Incorporation rate

引用本文复制引用

Christelle Machon,Jérôme Guitton,Frédéric Catez,Nicole Dalla Venezia,Floriane Vanhalle,Laetitia Guyot,Anne Vincent,Maxime Garcia,Béatrice Roy,Jean-Jacques Diaz..Study of intracellular anabolism of 5-fluorouracil and incorporation in nucleic acids based on an LC-HRMS method[J].药物分析学报（英文）,2021,11(1):77-87,11.

基金项目

This work was supported by Institut National Du Cancer(grant number 2018-131). （grant number 2018-131）

药物分析学报（英文）

OASCI

ISSN：2095-1779

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