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Stress increases MHC-I expression in dopaminergic neurons and induces autoimmune activation in Parkinson's disease

Bao-Yan Wang Yong-Yi Ye Chen Qian Hong-Bo Zhang Heng-Xu Mao Long-Ping Yao Xiang Sun Guo-Hui Lu Shi-Zhong Zhang

中国神经再生研究（英文版）2021，Vol.16Issue(12)：2521-2527,7.

Stress increases MHC-I expression in dopaminergic neurons and induces autoimmune activation in Parkinson's disease

Bao-Yan Wang ¹Yong-Yi Ye ²Chen Qian ¹Hong-Bo Zhang ¹Heng-Xu Mao ¹Long-Ping Yao ¹Xiang Sun ¹Guo-Hui Lu ³Shi-Zhong Zhang¹

作者信息

1. The National Key Clinical Specialty, The Engineering Technology Research Center of Education Ministry of China, Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration, Department of Neurosurgery, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong Province, China
2. Department of Neurosurgery, the Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong Province, China
3. Department of Neurosurgery, First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi Province, China
折叠

摘要

关键词

antigen presentation/autoimmune/CD8+ T cell/dopaminergic neuron/major histocompatibility complex class Ⅰ/mitochondria/neuroinflammation/oxidative stress/Parkinson's disease/PINK1

Key words

分类

医药卫生

引用本文复制引用

Bao-Yan Wang,Yong-Yi Ye,Chen Qian,Hong-Bo Zhang,Heng-Xu Mao,Long-Ping Yao,Xiang Sun,Guo-Hui Lu,Shi-Zhong Zhang..Stress increases MHC-I expression in dopaminergic neurons and induces autoimmune activation in Parkinson's disease[J].中国神经再生研究（英文版）,2021,16(12):2521-2527,7.

基金项目

This work was supported by the National Natural Science Foundation of China,Nos.81671240(to SZZ),81560220(to GHL) （to SZZ）

the Youth Science Foundation of Jiangxi Province of China,No.20151BAB215014(to GHL) （to GHL）

and Health and Family Planning Commission of Jiangxi Province of China,No.20195109(to GHL). （to GHL）

中国神经再生研究（英文版）

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ISSN：1673-5374

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