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Gene therapy with caspase-3 small interfering RNA-nanoparticles is neuroprotective after optic nerve damage

Mohamed Tawfik Xiwei Zhang Lisa Grigartzik Peter Heiduschka Werner Hintz Petra Henrich-Noack Berend van Wachem Bernhard A.Sabel

中国神经再生研究（英文版）2021，Vol.16Issue(12)：2534-2541,8.

Gene therapy with caspase-3 small interfering RNA-nanoparticles is neuroprotective after optic nerve damage

Mohamed Tawfik ¹Xiwei Zhang ²Lisa Grigartzik ¹Peter Heiduschka ³Werner Hintz ²Petra Henrich-Noack ¹Berend van Wachem ⁴Bernhard A.Sabel²

作者信息

1. Institute of Medical Psychology, Otto von Guericke University of Magdeburg, Magdeburg, Germany
2. Institute of Process Engineering, Otto von Guericke University of Magdeburg, Magdeburg, Germany
3. Department of Ophthalmology, Münster University Hospital, Münster, Germany
4. Department of Neurology with Institute of Translational Neurology, Münster University Hospital, Münster, Germany
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摘要

关键词

apoptosis/brain/caspase-3/drug delivery/gene therapy/in vivo confocal neuroimaging/nanoparticles/neurodegeneration/neuroprotection/retina/siRNA

Key words

apoptosis/brain/caspase-3/drug delivery/gene therapy/in vivo confocal neuroimaging/nanoparticles/neurodegeneration/neuroprotection/retina/siRNA

分类

医药卫生

引用本文复制引用

Mohamed Tawfik,Xiwei Zhang,Lisa Grigartzik,Peter Heiduschka,Werner Hintz,Petra Henrich-Noack,Berend van Wachem,Bernhard A.Sabel..Gene therapy with caspase-3 small interfering RNA-nanoparticles is neuroprotective after optic nerve damage[J].中国神经再生研究（英文版）,2021,16(12):2534-2541,8.

基金项目

MT was funded by the Leistungsorientierte Mittelvergabe(LOM)scholarship offered by the medical faculty of Magdeburg and the Deutscher Akademischer Austauschdienst(DAAD). （LOM）

中国神经再生研究（英文版）

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ISSN：1673-5374

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