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Designing and generating a mouse model: frequently asked questions

Channabasavaiah B.Gurumurthy Thomas L.Saunders Masato Ohtsuka

生物医学研究杂志（英文版）2021，Vol.35Issue(2)：76-90,15.

Designing and generating a mouse model: frequently asked questions

Channabasavaiah B.Gurumurthy ¹Thomas L.Saunders ²Masato Ohtsuka³

作者信息

1. Department of Pharmacology and Experimental Neuroscience, College of Medicine, University of Nebraska Medical Center, Omaha, NE 68106-5915, USA
2. Mouse Genome Engineering Core Facility, Department of Pharmacology and Experimental Neuroscience, College of Medicine, University of Nebraska Medical Center, Omaha, NE 68106-5915, USA
3. Department of Internal Medicine, Division of Genetic Medicine, University of Michigan Medical School, Ann Arbor, MI48109, USA
折叠

摘要

关键词

CRISPR/transgenic mouse/genetic engineering/knockout mouse/conditional knockout mouse/knock-in mouse

Key words

CRISPR/transgenic mouse/genetic engineering/knockout mouse/conditional knockout mouse/knock-in mouse

分类

生物科学

引用本文复制引用

Channabasavaiah B.Gurumurthy,Thomas L.Saunders,Masato Ohtsuka..Designing and generating a mouse model: frequently asked questions[J].生物医学研究杂志（英文版）,2021,35(2):76-90,15.

基金项目

We thank D.D.Meigs (University of Nebraska Medical Center) and Tonya Cejka (freelance English editor) for editing assistance.C.B.G.is funded by NIH grants R35HG010719,R21GM129559,R21AI143394 and R21DA046831.M.O.is funded by 2016-2017 Tokai University School of Medicine Project Research,the Research Aid from the Institute of Medical Sciences in Tokai University,Grant-in-Aid for Scientific Research (25290035) from MEXT,and a Grant-in-Aid for Challenging Exploratory Research (15K14371) from JSPS. （University of Nebraska Medical Center）

生物医学研究杂志（英文版）

OACSCD

ISSN：1674-8301

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