中国病理生理杂志2021，Vol.37Issue(5)：921-927,7.DOI:10.3969/j.issn.1000-4718.2021.05.020
子宫内膜异位症中箈络细胞的识别及形态特征
Identification and morphological features of telocytes in endometriosis
摘要
Abstract
AIM:To investigate the distribution and morphological features of telocytes(TCs)in the tissues of patients with ovarian endometriosis(Ems). METHODS:The tissue specimens from patients with ovarian cyst were har-vested,and diagnosed as Ems by hematoxylin-eosin(HE)staining. Simultaneously,ultrathin sections of the tissues were observed under transmission electron microscope(TEM). RESULTS:The ectopic endometrium was observed in the fo-cus of the ovarian cyst by HE staining,so that Ems was diagnosed. The results showed that TCs were indeed present in ovarian Ems under TEM. TCs with small cell bodies extended specific long,thin and moniliform telopodes(Tps)which had thick and thin parts(namely podoms and podomers,respectively). Moreover,podoms contained many organelles, such as endoplasmic reticulum and mitochondria. It was found that TCs in Ems had significant autophagosomes and lipid droplet. Furthermore,TCs formed a network through direct contact via long Tps and indirect contact via vesicles. CON-CLUSION:The TCs exist in ovarian Ems and their morphological features were demonstrated by TEM. This study pro-vides an original structural and functional perspective for the cellular components of ovarian Ems and improves our compre-hesion of the pathological aspects of Ems.关键词
子宫内膜异位症/箈络细胞/透射电子显微术Key words
Endometriosis/Telocytes/Transmission electron microscopy分类
医药卫生引用本文复制引用
徐婷,朱芝玲,吴彩琴,柯俊雅,张红旗..子宫内膜异位症中箈络细胞的识别及形态特征[J].中国病理生理杂志,2021,37(5):921-927,7.基金项目
Supported by Shanghai Natural Scientific Foundation(No.16ZR1403600) （No.16ZR1403600）
