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首页|期刊导航|中华医学杂志(英文版)|Immunogenicity and safety of a severe acute respiratory syndrome coronavirus 2 inactivated vaccine in healthy adults:randomized,double-blind,and placebo-controlled phase 1 and phase 2 clinical trials

Immunogenicity and safety of a severe acute respiratory syndrome coronavirus 2 inactivated vaccine in healthy adults:randomized,double-blind,and placebo-controlled phase 1 and phase 2 clinical trials

Hong-Xing Pan Jing-Xin Li Dan-Dan Zhu Jing-Liang Wu Xiao-Yu Xu Li Zhang Meng Wang Wen-Jie Tan Wei-Jin Huang Feng-Cai Zhu Jian-Kai Liu Bao-Ying Huang Gui-Fan Li Xian-Yun Chang Ya-Fei Liu Wen-Ling Wang Kai Chu Jia-Lei Hu

中华医学杂志(英文版)2021,Vol.134Issue(11):1289-1298,10.
中华医学杂志(英文版)2021,Vol.134Issue(11):1289-1298,10.DOI:10.1097/CM9.0000000000001573

Immunogenicity and safety of a severe acute respiratory syndrome coronavirus 2 inactivated vaccine in healthy adults:randomized,double-blind,and placebo-controlled phase 1 and phase 2 clinical trials

Immunogenicity and safety of a severe acute respiratory syndrome coronavirus 2 inactivated vaccine in healthy adults:randomized,double-blind,and placebo-controlled phase 1 and phase 2 clinical trials

Hong-Xing Pan 1Jing-Xin Li 1Dan-Dan Zhu 2Jing-Liang Wu 2Xiao-Yu Xu 3Li Zhang 4Meng Wang 4Wen-Jie Tan 5Wei-Jin Huang 4Feng-Cai Zhu 1Jian-Kai Liu 6Bao-Ying Huang 7Gui-Fan Li 5Xian-Yun Chang 8Ya-Fei Liu 8Wen-Ling Wang 8Kai Chu 5Jia-Lei Hu1

作者信息

  • 1. NHC Key Laboratory of Enteric Pathogenic Microbiology (Jiangsu Provincial Center for Disease Control and Prevention),Nanjing,Jiangsu 210009,China
  • 2. Huaiyin District Center for Disease Control and Prevention,Huai'an,Jiangsu 223003,China
  • 3. Vazyme Biotech Co.,Ltd,Nanjing,Jiangsu 210000,China
  • 4. National Institutes for Food and Drug Control,Beijing 102629,China
  • 5. NHC Key Laboratory of Biosafety,National Institute for Viral Disease Control and Prevention,Chinese Center for Disease Control and Prevention,Beijing 102206,China
  • 6. Center for Global Health,Nanjing Medical University,Nanjing,Jiangsu 211166,China
  • 7. Shenzhen Kangtai Biological Products Co.,Ltd.,Shenzhen,Guangdong 518057,China
  • 8. Beijing Minhai Biological Technology Co.,Ltd.,Beijing 102600,China
  • 折叠

摘要

关键词

Immunogenicity/Safety/SARS-CoV-2/Inactivated vaccine/Neutralizing antibody

Key words

Immunogenicity/Safety/SARS-CoV-2/Inactivated vaccine/Neutralizing antibody

引用本文复制引用

Hong-Xing Pan,Jing-Xin Li,Dan-Dan Zhu,Jing-Liang Wu,Xiao-Yu Xu,Li Zhang,Meng Wang,Wen-Jie Tan,Wei-Jin Huang,Feng-Cai Zhu,Jian-Kai Liu,Bao-Ying Huang,Gui-Fan Li,Xian-Yun Chang,Ya-Fei Liu,Wen-Ling Wang,Kai Chu,Jia-Lei Hu..Immunogenicity and safety of a severe acute respiratory syndrome coronavirus 2 inactivated vaccine in healthy adults:randomized,double-blind,and placebo-controlled phase 1 and phase 2 clinical trials[J].中华医学杂志(英文版),2021,134(11):1289-1298,10.

基金项目

The authors appreciate the contributions of all inves-tigators at the Jiangsu Provincial Center for Disease Control and Prevention (CDC) and Huaiyin CDC who worked on the trials.The authors thank Yuan-Zheng Qiu for helpful expert advice and support for writing.We would like to thank all the participants who volunteered for this study.This study was supported by grants from the Guangdong Emergency Program for Prevention and Control of COVID-19 (No.2020A1111340002) and the Shenzhen Key Research Project for Prevention and Control of COVID-19. (CDC)

中华医学杂志(英文版)

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