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Time-Programmed Delivery of Sorafenib and Anti-CD47 Antibody via a Double-Layer-Gel Matrix for Postsurgical Treatment of Breast Cancer

Liping Huang Yiyi Zhang Yanan Li Fanling Meng Hongyu Li Huimin Zhang Jiasheng Tu Chunmeng Sun Liang Luo

纳微快报（英文）2021，Vol.13Issue(9)：353-367,15.

Time-Programmed Delivery of Sorafenib and Anti-CD47 Antibody via a Double-Layer-Gel Matrix for Postsurgical Treatment of Breast Cancer

Liping Huang ¹Yiyi Zhang ¹Yanan Li ²Fanling Meng ³Hongyu Li ¹Huimin Zhang ⁴Jiasheng Tu ¹Chunmeng Sun ¹Liang Luo²

作者信息

1. College of Life Science and Technology,National Engineering Research Center for Nanomedicine,Huazhong University of Science and Technology,Wuhan 430074,People's Republic of China
2. State Key Laboratory of Natural Medicines,NMPA Key Laboratory for Research and Evaluation of Pharmaceutical Preparations and Excipients,and Department of Pharmaceutics,School of Pharmacy,China Pharmaceutical University,24 Tong Jia Xiang,Nanjing 210009,China
3. School of Food Science and Pharmaceutical Engineering,Nanjing Normal University,Nanjing 210023,People's Republic of China
4. Hubei Key Laboratory of Bioinorganic Chemistry and Materia Medica,School of Chemistry and Chemical Engineering,Huazhong University of Science and Technology,Wuhan 430074,People's Republic of China
折叠

摘要

关键词

Hierarchical hydrogel/Sorafenib/Postoperative immunosuppression reversal/Tumor-associated macrophages/Anti-CD47 antibody

Key words

Hierarchical hydrogel/Sorafenib/Postoperative immunosuppression reversal/Tumor-associated macrophages/Anti-CD47 antibody

引用本文复制引用

Liping Huang,Yiyi Zhang,Yanan Li,Fanling Meng,Hongyu Li,Huimin Zhang,Jiasheng Tu,Chunmeng Sun,Liang Luo..Time-Programmed Delivery of Sorafenib and Anti-CD47 Antibody via a Double-Layer-Gel Matrix for Postsurgical Treatment of Breast Cancer[J].纳微快报（英文）,2021,13(9):353-367,15.

基金项目

This work was funded by the budg-ets from the National Basic Research Plan of China(2018YFA0208903),National Natural Science Foundation of China (21877042,22077038,81972894,81673364),the Minis-try of Science and Technology of the People's Republic of China(2017ZX09101001006),the Fundamental Research Funds for the Central Universities (2632018ZD13),the startup fund of Huazhong University of Science and Technology,and the Priority Academic Program Development of Jiangsu Higher Education Institutions.The authors also thank the assistance from the Research Core Facilities for Life Science (HUST). （2018YFA0208903）

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ISSN：2311-6706

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