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PINK1 gene mutation by pair truncated sgRNA/Cas9-D10A in cynomolgus monkeys

Zhen-Zhen Chen Yu-Yu Niu Jian-Ying Wang Yu Kang Qiao-Yan Yang Xue-Ying Gu Da-Long Zhi Li Yan Cheng-Zu Long Bin Shen

动物学研究2021，Vol.42Issue(4)：469-477,9.

PINK1 gene mutation by pair truncated sgRNA/Cas9-D10A in cynomolgus monkeys

Zhen-Zhen Chen ¹Yu-Yu Niu ²Jian-Ying Wang ¹Yu Kang ²Qiao-Yan Yang ³Xue-Ying Gu ¹Da-Long Zhi ²Li Yan ⁴Cheng-Zu Long ³Bin Shen²

作者信息

1. Faculty of Life Science and Technology,Kunming University of Science and Technology,Kunming,Yunnan 650500,China
2. State Key Laboratory of Primate Biomedical Research,Institute of Primate Translational Medicine,Kunming University of Science and Technology,Kunming,Yunnan 650500,China
3. State Key Laboratory of Reproductive Medicine,Department of Prenatal Diagnosis,Women's Hospital of Nanjing Medical University,Nanjing Maternity and Child Health Hospital,Nanjing Medical University,Nanjing,Jiangsu 211166,China
4. Leon H Charney Division of Cardiology,New York University School of Medicine,New York,NY 10016,USA
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摘要

关键词

Cas9-D10A/Cynomolgus/PINK1

Key words

Cas9-D10A/Cynomolgus/PINK1

引用本文复制引用

Zhen-Zhen Chen,Yu-Yu Niu,Jian-Ying Wang,Yu Kang,Qiao-Yan Yang,Xue-Ying Gu,Da-Long Zhi,Li Yan,Cheng-Zu Long,Bin Shen..PINK1 gene mutation by pair truncated sgRNA/Cas9-D10A in cynomolgus monkeys[J].动物学研究,2021,42(4):469-477,9.

基金项目

This research was supported by the National Key Research and Development Program(2016YFA0101401 and 2018YFA0801400)and Major Basic Research Project of Science and Technology of Yunnan(2019FY002 and 202001BC070001) （2016YFA0101401 and 2018YFA0801400）

动物学研究

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ISSN：0254-5853

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