农药学学报2021，Vol.23Issue(4)：668-679,12.DOI:10.16801/j.issn.1008-7303.2021.0114
草地贪夜蛾性信息素的合成
Synthesis of the sex pheromones of Spodoptera frugiperda (J. E, Smith)
摘要
Abstract
The sex pheromone of Spodoptera frugiperda (J. E, Smith), has the advantages of the safety to the environment and the natural enemies, and without insecticides resistance. Its active components included (Z)-dodec-7-en-1-yl acetate, (Z)-dodec-9-en-1-yl acetate, (Z)-tetradec-9-en-1-yl acetate, (Z)-hexadec-11-en-1-yl acetate, (E)-dodec-7-en-1-yl acetate and (9Z,12E)-tetradeca-9,12-dien-1-yl acetate. The novel, efficient and concise synthesis of S. frugiperda (J. E, Smith) sex pheromones has been achieved. The key steps of this synthetic approach involved Wittig coupling of aldehyde with functionalized phosphomium salt, the alkylation of alkynes, and Knoevenagel condensation reaction of malonic acid with propionic aldehyde. Furthermore, the Wittig reaction of hydroxy-bearing phosphomium salt and Knoevenagel condensation reaction were firstly applied to the synthesis of S. frugiperda (J. E, Smith) sex pheromones.关键词
草地贪夜蛾/信息素合成/官能团化鏻盐/Knoevenagel缩合反应Key words
Spodoptera frugiperda (J. E, Smith)/synthesis of pheromones/functionalized phosphomium salt/Knoevenagel condensation reaction分类
农业科技引用本文复制引用
王雪扬,孙效,马思捷,原超楠,袁谷城,边庆花,王敏,钟江春..草地贪夜蛾性信息素的合成[J].农药学学报,2021,23(4):668-679,12.基金项目
The National Key Research and Development Program of China(2017YFD0201404). （2017YFD0201404）
