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Simultaneous determination of fourteen components of Gumiganghwal-tang tablet in human plasma by UPLC-ESI-MS/MS and its application to pharmacokinetic study

Seung-Hyun Jeong Ji-Hun Jang Guk-Yeo Lee Seung-Jung Yang Hea-Young Cho Yong-Bok Lee

药物分析学报(英文)2021,Vol.11Issue(4):444-457,14.
药物分析学报(英文)2021,Vol.11Issue(4):444-457,14.

Simultaneous determination of fourteen components of Gumiganghwal-tang tablet in human plasma by UPLC-ESI-MS/MS and its application to pharmacokinetic study

Simultaneous determination of fourteen components of Gumiganghwal-tang tablet in human plasma by UPLC-ESI-MS/MS and its application to pharmacokinetic study

Seung-Hyun Jeong 1Ji-Hun Jang 1Guk-Yeo Lee 2Seung-Jung Yang 3Hea-Young Cho 4Yong-Bok Lee1

作者信息

  • 1. College of Pharmacy,Chonnam National University,77 Yongbong-ro,Buk-gu,Gwangju,61186,Republic of Korea
  • 2. National Development Institute of Korean Medicine,288 Udeuraendeu-gil,Anyang-myeon,Jangheung-gun,Jeollanam-do,59338,Republic of Korea
  • 3. Department of Oriental Rehabilitation Medicine,Dongshin University Gwangju Korean Medicine Hospital,141 Wolsan-ro,Nam-gu,Gwangju,61619,Republic of Korea
  • 4. College of Pharmacy,CHA University,335 Pangyo-ro,Bundang-gu,Seongnam-si,Gyeonggi-do,13488,Republic of Korea
  • 折叠

摘要

关键词

Gumiganghwal-tang/Fourteen bioactive ingredients/Simultaneous analysis/UPLC-ESI-MS/MS/Pharmacokinetics/Clinical study

Key words

Gumiganghwal-tang/Fourteen bioactive ingredients/Simultaneous analysis/UPLC-ESI-MS/MS/Pharmacokinetics/Clinical study

引用本文复制引用

Seung-Hyun Jeong,Ji-Hun Jang,Guk-Yeo Lee,Seung-Jung Yang,Hea-Young Cho,Yong-Bok Lee..Simultaneous determination of fourteen components of Gumiganghwal-tang tablet in human plasma by UPLC-ESI-MS/MS and its application to pharmacokinetic study[J].药物分析学报(英文),2021,11(4):444-457,14.

基金项目

This work was supported by a grant from the National Devel-opment Institute of Korean Medicine (NIKOM) funded by the Korean Ministry of Health and Welfare (MOHW),Republic of Korea. (NIKOM)

药物分析学报(英文)

OASCI

2095-1779

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