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H3K36 methyltransferase NSD1 regulates chondrocyte differentiation for skeletal development and fracture repair

Rui Shao Zhong Zhang Zhan Xu Huiling Ouyang Lijun Wang Hongwei Ouyang Matthew Greenblatt Xi Chen Weiguo Zou

骨研究(英文版)2021,Vol.9Issue(3):349-359,11.
骨研究(英文版)2021,Vol.9Issue(3):349-359,11.

H3K36 methyltransferase NSD1 regulates chondrocyte differentiation for skeletal development and fracture repair

H3K36 methyltransferase NSD1 regulates chondrocyte differentiation for skeletal development and fracture repair

Rui Shao 1Zhong Zhang 2Zhan Xu 2Huiling Ouyang 2Lijun Wang 2Hongwei Ouyang 2Matthew Greenblatt 3Xi Chen 4Weiguo Zou5

作者信息

  • 1. Shanghai Institute of Microsurgery on Extremities,and Department of Orthopedic Surgery,Shanghai Jiao Tong University Affiliated Sixth People's Hospital,Shanghai,China
  • 2. State Key Laboratory of Cell Biology,Shanghai Institute of Biochemistry and Cell Biology,CAS Center for Excellence in Molecular Cell Sciences,Chinese Academy of Sciences,University of Chinese Academy of Sciences,Shanghai,China
  • 3. Li Dak Sum&Yip Yio Chin Center for Stem Cell and Regenerative Medicine,Zhejiang University-University of Edinburgh Institute,Zhejiang University,Hangzhou,Zhejiang,China
  • 4. China Orthopedic Regenerative Medicine Group,Hangzhou,Zhejiang,China
  • 5. Department of Pathology and Laboratory Medicine,Weill Cornell Medicine,New York,NY,USA
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摘要

引用本文复制引用

Rui Shao,Zhong Zhang,Zhan Xu,Huiling Ouyang,Lijun Wang,Hongwei Ouyang,Matthew Greenblatt,Xi Chen,Weiguo Zou..H3K36 methyltransferase NSD1 regulates chondrocyte differentiation for skeletal development and fracture repair[J].骨研究(英文版),2021,9(3):349-359,11.

基金项目

The authors would like to thank Dr.Andrew McMahon(Harvard University,Boston)for providing the Prx1-Cre mouse line and Dr.Xiao Yang(Affiliated Hospital of Academy of Military Medical Sciences,Beijing)for providing the Col2-Cre mouse line.The authors would like to thank members of the Zou Lab for helpful discussions.This work was supported by grants from the National Natural Science Foundation of China(NSFC)[81902212,81725010,81672119,81991512],Strategic Priority Research Program of the Chinese Academy of Sciences[XDB19000000],Major Program of Development Fund for Shanghai Zhangjiang National Innovation Demonstration Zone[ZJ2018-ZD-004]. (Harvard University,Boston)

骨研究(英文版)

OACSCDSCI

2095-4700

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