首页|期刊导航|药物分析学报(英文)|Transformation of berberine to its demethylated metabolites by the CYP51 enzyme in the gut microbiota
药物分析学报(英文)2021,Vol.11Issue(5):628-637,10.
Transformation of berberine to its demethylated metabolites by the CYP51 enzyme in the gut microbiota
Transformation of berberine to its demethylated metabolites by the CYP51 enzyme in the gut microbiota
摘要
关键词
Berberine/Biotransformation/Gut microbiota/CYP51/Demethylated metaboliteKey words
Berberine/Biotransformation/Gut microbiota/CYP51/Demethylated metabolite引用本文复制引用
Zheng-Wei Zhang,Jian-Dong Jiang,Lin Cong,Ran Peng,Pei Han,Shu-Rong Ma,Li-Bin Pan,Jie Fu,Hang Yu,Yan Wang..Transformation of berberine to its demethylated metabolites by the CYP51 enzyme in the gut microbiota[J].药物分析学报(英文),2021,11(5):628-637,10.基金项目
The project was supported by CAMS Innovation Fund for Med-ical Sciences(CIFMS,Grant No.:2016-I2M-3-011,China),the Na-tional Natural Science Foundation of China(Grant Nos.:81803613 and 81973290),Beijing Key Laboratory of Non-Clinical Drug Metabolism and PK/PD study(Grant No.:Z141102004414062,China),Beijing Natural Sciences Fund Key Projects(Grant No.:7181007)and the National Megaproject for Innovative Drugs(Grant No.:2018ZX09711001-002-002).We would like to thank Shimadzu(China)Co.,Ltd.for technological support. (CIFMS,Grant No.:2016-I2M-3-011,China)