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Using transcriptome Shannon entropy to evaluate the off-target effects and safety of insecticidal siRNAs

MA Wei-hua HE Kang LI Fei WU Tong ZHANG Zan LI Hang SITU Gong-ming YIN Chuan-lin YE Xin-hai CHEN Meng-yao ZHAO Xian-xin

农业科学学报（英文）2022，Vol.21Issue(1)：170-177,8.

农业科学学报（英文）2022，Vol.21Issue(1)：170-177,8.DOI:10.1016/S2095-3119(20)63394-9

Using transcriptome Shannon entropy to evaluate the off-target effects and safety of insecticidal siRNAs

MA Wei-hua ¹HE Kang ²LI Fei ²WU Tong ¹ZHANG Zan ²LI Hang ³SITU Gong-ming ³YIN Chuan-lin ³YE Xin-hai ²CHEN Meng-yao ²ZHAO Xian-xin²

作者信息

1. College of Plant Science and Technology,Huazhong Agricultural University,Wuhan 430070,P.R.China
2. State Key Laboratory of Rice Biology/Ministry of Agricultural and Rural Affairs Key Laboratory of Molecular Biology of Crop Pathogens and Insect Pests/Institute of Insect Sciences,Zhejiang University,Hangzhou 310058,P.R.China
3. College of Plant Protection,Nanjing Agricultural University,Nanjing 210095,P.R.China
折叠

摘要

关键词

RNAi/off-target effect/transcriptome entropy/non-target organisms/RNAi-mediated pest management

Key words

RNAi/off-target effect/transcriptome entropy/non-target organisms/RNAi-mediated pest management

引用本文复制引用

MA Wei-hua,HE Kang,LI Fei,WU Tong,ZHANG Zan,LI Hang,SITU Gong-ming,YIN Chuan-lin,YE Xin-hai,CHEN Meng-yao,ZHAO Xian-xin..Using transcriptome Shannon entropy to evaluate the off-target effects and safety of insecticidal siRNAs[J].农业科学学报（英文）,2022,21(1):170-177,8.

基金项目

This work was funded by grants from the National Science and Technology Major Project of China(2016ZX08011002).We also thank the DBMediting Company for professional English language editing services.The authors have declared that no competing interest exists. （2016ZX08011002）

农业科学学报（英文）

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ISSN：2095-3119

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