首页|期刊导航|光：科学与应用（英文版）|Microglia modulation with 1070-nm light attenuates Aβ burden and cognitive impairment in Alzheimer's disease mouse model

Microglia modulation with 1070-nm light attenuates Aβ burden and cognitive impairment in Alzheimer's disease mouse model

Lechan Tao Liang Chen Xiaoling Gao Xunbin Wei Qi Liu Fuli Zhang Yuting Fu Xi Zhu Xiaofu Weng Hongbin Han Yong Huang Yuanzhen Suo

光：科学与应用（英文版）2021，Vol.10Issue(10)：1863-1876,14.

Microglia modulation with 1070-nm light attenuates Aβ burden and cognitive impairment in Alzheimer's disease mouse model

Lechan Tao ¹Liang Chen ²Xiaoling Gao ³Xunbin Wei ⁴Qi Liu ¹Fuli Zhang ⁵Yuting Fu ⁶Xi Zhu ⁷Xiaofu Weng ¹Hongbin Han ¹Yong Huang ¹Yuanzhen Suo¹

作者信息

1. State Key Laboratory of Oncogenes and Related Genes,Shanghai Cancer Institute,Med-X Research Institute and School of Biomedical Engineering,Shanghai Jiao Tong University,Shanghai 200030,China
2. Department of Neurosurgery,Huashan Hospital,Shanghai Medical College,Fudan University,Shanghai 200040,China
3. Tianqiao and Chrissy Chen Institute for Clinical Translational Research,Huashan Hospital,Shanghai 200040,China
4. Department of Pharmacology and Chemical Biology,State Key Laboratory of Oncogenes and Related Genes,Shanghai Universities Collaborative Innovation Center for Translational Medicine,Shanghai Jiao Tong University School of Medicine,Shanghai 200025,China
5. Institute of Medical Technology,Peking University Health Science Center,Beijing 100191,China
6. Biomedical Engineering Department,Peking University,Beijing 100081,China
7. Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education/Beijing),Peking University Cancer Hospital&Institute,Beijing 100142,China
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摘要

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Lechan Tao,Liang Chen,Xiaoling Gao,Xunbin Wei,Qi Liu,Fuli Zhang,Yuting Fu,Xi Zhu,Xiaofu Weng,Hongbin Han,Yong Huang,Yuanzhen Suo..Microglia modulation with 1070-nm light attenuates Aβ burden and cognitive impairment in Alzheimer's disease mouse model[J].光：科学与应用（英文版）,2021,10(10):1863-1876,14.

基金项目

This work was supported by grants from the National Key Research and Development Program of China(Grant No.2019YFC1604604),the Special Fund for Research on National Major Research Instruments of China(Grant No.62027824),the National Science Fund for Distinguished Young Scholars(Grant No.61425006),the SJTU Medicine Engineering Interdisciplinary Research Fund(Grant No.YG2017MS19),the Program of Shanghai Technology Research Leader(Grant No.17XD1402200),the Fundamental Research Funds for the Central Universities(Grant No.81661168014),the project of Innovative Research Team of High-level Local Universities in Shanghai,Talents Program of Shanghai Municipal Health Commission(Chen Liang,Grant No.2018BR06)and the National Natural Science Foundation of China(Grant No.92068111,81973272,82073836,61975118,and 62075013).We thank Professor Hao He and Professor Bobo Gu for helpful discussions.We thank Meilu Tian for improving the grammar of the manuscript.We also thank Professor Guoyuan Yang and his students for providing the MWM. （Grant No.2019YFC1604604）

光：科学与应用（英文版）

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ISSN：2095-5545

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