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Overexpression of Lrp5 enhanced the anti-breast cancer effects of osteocytes in bone

Shengzhi Liu Nicole Vike Fangjia Li Joseph Rispoli Akihiro Sudo Jing Liu Alexander Robling Harikrishna Nakshatri Bai-Yan Li Hiroki Yokota Di Wu Xun Sun Yao Fan Rongrong Zha Aydin Jalali Yan Feng Kexin Li Tomohiko Sano

骨研究（英文版）2021，Vol.9Issue(4)：494-506,13.

Overexpression of Lrp5 enhanced the anti-breast cancer effects of osteocytes in bone

Shengzhi Liu ¹Nicole Vike ²Fangjia Li ³Joseph Rispoli ²Akihiro Sudo ⁴Jing Liu ³Alexander Robling ⁵Harikrishna Nakshatri ⁶Bai-Yan Li ⁷Hiroki Yokota ⁸Di Wu ⁹Xun Sun ¹Yao Fan ⁹Rongrong Zha ⁵Aydin Jalali ⁶Yan Feng ⁸Kexin Li ¹Tomohiko Sano⁹

作者信息

1. Department of Biomedical Engineering,Indiana University Purdue University Indianapolis,Indianapolis,IN,USA
2. Weldon School of Biomedical Engineering,Purdue University,West Lafayette,IN,USA
3. Department of Physics,Indiana University Purdue University Indianapolis,Indianapolis,IN,USA
4. Department of Orthopedic Surgery,Mie University,Tsu,Mie,Japan
5. Department of Anatomy and Cell Biology,Indiana University School of Medicine,Indianapolis,IN,USA
6. Indiana Center for Musculoskeletal Health,Indiana University School of Medicine,Indianapolis,IN,USA
7. Department of Surgery,Indiana University School of Medicine,Indianapolis,IN,USA
8. Simon Cancer Center,Indiana University School of Medicine,Indianapolis,IN,USA
9. Department of Pharmacology,School of Pharmacy,Harbin Medical University,Harbin,China
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摘要

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Shengzhi Liu,Nicole Vike,Fangjia Li,Joseph Rispoli,Akihiro Sudo,Jing Liu,Alexander Robling,Harikrishna Nakshatri,Bai-Yan Li,Hiroki Yokota,Di Wu,Xun Sun,Yao Fan,Rongrong Zha,Aydin Jalali,Yan Feng,Kexin Li,Tomohiko Sano..Overexpression of Lrp5 enhanced the anti-breast cancer effects of osteocytes in bone[J].骨研究（英文版）,2021,9(4):494-506,13.

基金项目

The authors appreciate Andy Chen,April Hoggatt,Rahul Prakash,and Xinyu Zhao for technical support and Kazunori Hamamura for critical reading of the manuscript.This study was supported in part by funds from a breast cancer advocacy group,100 Voices of Hope(H.Y.),and the Indiana University Precision Health Initiative(H.N.),as well as NIH R01AR52144(H.Y.),R03CA238555(H.Y.),and R01AR053237(A.R.). （H.Y.）

骨研究（英文版）

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ISSN：2095-4700

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