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3D assessment of intervertebral disc degeneration in zebrafish identifies changes in bone density that prime disc disease

Erika Kague Stephen Cross C.Patrick Royall P.Eckhard Witten Chrissy L.Hammond Francesco Turci Elis Newman Yushi Yang Kate Robson Brown Mona S.Aglan Ghada A.Otaify Samia A.Temtamy Victor L.Ruiz-Perez

骨研究(英文版)2021,Vol.9Issue(4):521-536,16.
骨研究(英文版)2021,Vol.9Issue(4):521-536,16.

3D assessment of intervertebral disc degeneration in zebrafish identifies changes in bone density that prime disc disease

3D assessment of intervertebral disc degeneration in zebrafish identifies changes in bone density that prime disc disease

Erika Kague 1Stephen Cross 2C.Patrick Royall 3P.Eckhard Witten 4Chrissy L.Hammond 5Francesco Turci 1Elis Newman 3Yushi Yang 1Kate Robson Brown 3Mona S.Aglan 6Ghada A.Otaify 7Samia A.Temtamy 8Victor L.Ruiz-Perez9

作者信息

  • 1. School of Physiology,Pharmacology and Neuroscience,Biomedical Sciences,University of Bristol,Bristol,UK
  • 2. Wolfson Bioimaging Facility,Biomedical Sciences,University of Bristol,Bristol,UK
  • 3. School of Physics,HH Wills Physics Laboratory,University of Bristol,Bristol,UK
  • 4. School of Chemistry,University of Bristol,Bristol,UK
  • 5. Evolutionary Developmental Biology,Department of Biology,Ghent University,Ghent,Belgium
  • 6. Centre for Nanoscience and Quantum Information,University of Bristol,Bristol,UK
  • 7. Bristol Centre for Functional Nanomaterials,University of Bristol,Bristol,UK
  • 8. Department of Anthropology and Archaeology,University of Bristol,Bristol,UK
  • 9. Department of Mechanical Engineering,University of Bristol,Bristol,UK
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摘要

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Erika Kague,Stephen Cross,C.Patrick Royall,P.Eckhard Witten,Chrissy L.Hammond,Francesco Turci,Elis Newman,Yushi Yang,Kate Robson Brown,Mona S.Aglan,Ghada A.Otaify,Samia A.Temtamy,Victor L.Ruiz-Perez..3D assessment of intervertebral disc degeneration in zebrafish identifies changes in bone density that prime disc disease[J].骨研究(英文版),2021,9(4):521-536,16.

基金项目

E.K.and C.L.H were funded by Versus Arthritis(21937,21211).C.P.R.and F.T.acknowledge the European Research Council under the FP7/ERC(617266"NANOPRS").We thank Dr.Dominic Alibhai from the Wolfson Bioimaging Facility at the University of Bristol for his help with CTfire and all members for their support and assistance in this work.We acknowledge the Paul Scherrer Institut,Villigen,Switzerland for the provision of synchrotron radiation beamtime at the TOMCAT beamline of the Swiss Light Source. (21937,21211)

骨研究(英文版)

OACSCDSCI

2095-4700

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