国际眼科杂志2022，Vol.22Issue(2)：175-181,7.DOI:10.3980/j.issn.1672-5123.2022.2.01
OCTA评估糖尿病视网膜病变患者全视网膜激光光凝后黄斑区血流情况
Assessment of macular vascular network after panretinal photocoagulation in the patients with diabetic retinopathy by OCTA
邱奥望 1袁冬青 1朱鸿静 1顾晨烽 1刘庆淮 1张薇玮1
作者信息
- 1. 210029 中国江苏省南京市,南京医科大学第一附属医院(江苏省人民医院)眼科
- 折叠
摘要
Abstract
AIM: To evaluate the differences of macular vascular network measured by optical coherence tomography angiography ( OCTA ) between severe non-proliferative diabetic retinopathy ( S-NPDR) eyes and health eyes, and explore the changes of these OCTA characteristics in patients with S - NPDR before and after panretinal photocoagulation ( PRP) .METHODS: This was a prospective study including 31 eyes from 18 consecutive patients with S-NPDR and 31 eyes of healthy subjects. We measured macular vascular density and foveal avascular zone ( FAZ) area and volume by an OCTA device.RESULTS: Compared to the normal control group, in superficial retinal capillary plexus ( SCP ) , macular vascular density decreased in S- NPDR group, except foveal vascular density unchanged. Consistently, in deep retinal capillary plexus ( DCP ) , macular vascular density was also lower in S-NPDR group. In addition, FAZ area and volume expanded in S-NPDR eyes. At 6mo post-PRP in S-NPDR eyes, foveal SCP and DCP densities increased significantly, while FAZ area and volume decreased. At 3mo post - PRP, only foveal vascular density in DCP increased. The changes of foveal SCP and DCP densities as well as FAZ area and volume were not statically significant at 1mo post-PRP.CONCLUSION: Macular vascular network was impaired in S-NPDR assessed by OCTA. Although OCTA parameters were not significantly affected by PRP in 1 and 3mo period, at 6mo follow-up parameters became significant after PRP.关键词
全视网膜光凝术/黄斑血管密度/视网膜中心凹无血管区/糖尿病视网膜病变/光学相干断层血流成像技术(OCTA)Key words
panretinal photocoagulation/macular vascular density/foveal avascular zone/diabetic retinopathy/optical coherence tomography angiography ( OCTA)引用本文复制引用
邱奥望,袁冬青,朱鸿静,顾晨烽,刘庆淮,张薇玮..OCTA评估糖尿病视网膜病变患者全视网膜激光光凝后黄斑区血流情况[J].国际眼科杂志,2022,22(2):175-181,7.
