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A sandwich ELISA kit reveals marked elevation of titin N-terminal fragment levels in the urine of mdx mice

Taku Shirakawa Shoji Fukushima Masafumi Matsuo Ayumu Ikushima Nobuhiro Maruyama Yoshinori Nambu Hiroyuki Awano Kayo Osawa Kei Nirasawa Yoichi Negishi Hisahide Nishio

动物模型与实验医学（英文）2022，Vol.5Issue(1)：48-55,8.
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动物模型与实验医学（英文）2022，Vol.5Issue(1)：48-55,8.DOI:10.1002/ame2.12204

A sandwich ELISA kit reveals marked elevation of titin N-terminal fragment levels in the urine of mdx mice

A sandwich ELISA kit reveals marked elevation of titin N-terminal fragment levels in the urine of mdx mice

Taku Shirakawa 1Shoji Fukushima 2Masafumi Matsuo 3Ayumu Ikushima 1Nobuhiro Maruyama 2Yoshinori Nambu 3Hiroyuki Awano 4Kayo Osawa 5Kei Nirasawa 5Yoichi Negishi 6Hisahide Nishio7

作者信息

  • 1. Research Center for Locomotion Biology,Kobe Gakuin University,Kobe,Japan
  • 2. KNC Department of Nucleic Acid Drug Discovery,Faculty of Rehabilitation,Kobe Gakuin University,Kobe,Japan
  • 3. Department of Pharmaceutics,Faculty of Pharmaceutical Sciences,Kobe Gakuin University,Kobe,Japan
  • 4. Diagnostic&Research Reagents Division,Immuno-Biological Laboratories Co.,Ltd,Fujioka,Japan
  • 5. Department of Pediatrics,Kobe University Graduate School of Medicine,Kobe,Japan
  • 6. Department of Medical Technology, Faculty of Health Sciences,Kobe Tokiwa University,Kobe,Japan
  • 7. Department of Drug Delivery and Molecular Biopharmaceutics,School of Pharmacy,Tokyo University of Pharmacy and Life Sciences,Tokyo,Japan
  • 折叠

摘要

关键词

biomarker/Duchenne muscular dystrophy/ELISA/mdx mouse/titin/urine

Key words

biomarker/Duchenne muscular dystrophy/ELISA/mdx mouse/titin/urine

引用本文复制引用

Taku Shirakawa,Shoji Fukushima,Masafumi Matsuo,Ayumu Ikushima,Nobuhiro Maruyama,Yoshinori Nambu,Hiroyuki Awano,Kayo Osawa,Kei Nirasawa,Yoichi Negishi,Hisahide Nishio..A sandwich ELISA kit reveals marked elevation of titin N-terminal fragment levels in the urine of mdx mice[J].动物模型与实验医学（英文）,2022,5(1):48-55,8.

基金项目

This study was supported in part by the Practical Research Project for Rare/Intractable Diseases from the Japan Agency for Medical Research and Development(AMED （）

20314714 to M.M.). （）

动物模型与实验医学（英文）

OACSCD

2096-5451

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