首页|期刊导航|药物分析学报（英文）|Novel insights into conjugation of antitumor-active unsymmetrical bisacridine C-2028 with glutathione:Characteristics of non-enzymatic and glutathione S-transferase-mediated reactions
药物分析学报（英文）2021，Vol.11Issue(6)：791-798,8.
Novel insights into conjugation of antitumor-active unsymmetrical bisacridine C-2028 with glutathione:Characteristics of non-enzymatic and glutathione S-transferase-mediated reactions
Novel insights into conjugation of antitumor-active unsymmetrical bisacridine C-2028 with glutathione:Characteristics of non-enzymatic and glutathione S-transferase-mediated reactions
摘要
关键词
Antitumor agent/Unsymmetrical bisacridine/Metabolic detoxification/Glutathione S-Conjugate/Glutathione S-transferase/Non-enzymatic conjugationKey words
Antitumor agent/Unsymmetrical bisacridine/Metabolic detoxification/Glutathione S-Conjugate/Glutathione S-transferase/Non-enzymatic conjugation引用本文复制引用
Agnieszka Pot(e)ga,Michat Kosno,Zofia Mazerska..Novel insights into conjugation of antitumor-active unsymmetrical bisacridine C-2028 with glutathione:Characteristics of non-enzymatic and glutathione S-transferase-mediated reactions[J].药物分析学报（英文）,2021,11(6):791-798,8.基金项目
The authors wish to thank Dr.Ewa Paluszkiewicz (Department of Pharmaceutical Technology and Biochemistry,Faculty of Chem-istry,Gda(n)sk University of Technology,Gda(n)sk,Poland) for the synthesis of the C-2028 compound performed according to the procedures described in patents.We are grateful to Dr.Weronika Hewelt-Belka (Department of Analytical Chemistry,Faculty of Chemistry,Gda(n)sk University of Technology,Gda(n)sk,Poland) for her help in the field of MS(/MS) analysis.Acknowledgments are also given to the Shim-pol A.M.Borzymowski Company (Warsaw,Poland) for supplying the Nexera-I LC-2040C 3D and LCMS-2020 systems,and for their technical assistance. （Department of Pharmaceutical Technology and Biochemistry,Faculty of Chem-istry,Gda(n）
