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Polarization modulation with optical lock-in detection reveals universal fluorescence anisotropy of subcellular structures in live cells

Meiling Guan Zhenli Jing Micheal Q.Zhang Dayong Jin Peng Xi Juntao Gao Miaoyan Wang Karl Zhanghao Xu Zhang Meiqi Li Wenhui Liu Jing Niu Xusan Yang Long Chen

光：科学与应用（英文版）2022，Vol.11Issue(1)：50-62,13.

Polarization modulation with optical lock-in detection reveals universal fluorescence anisotropy of subcellular structures in live cells

Meiling Guan ¹Zhenli Jing ²Micheal Q.Zhang ²Dayong Jin ³Peng Xi ⁴Juntao Gao ⁵Miaoyan Wang ⁶Karl Zhanghao ¹Xu Zhang ⁵Meiqi Li ⁷Wenhui Liu ²Jing Niu ⁸Xusan Yang ⁹Long Chen¹

作者信息

1. Department of Biomedical Engineering,College of Future Technology,Peking University,Beijing 100871,China
2. MOE Key Laboratory of Bioinformatics,Bioinformatics Division,Center for Synthetic & Systems Biology,BNRist,Beijing,China
3. Department of Biological Sciences and Center for System Biology,The University of Texas at Dallas,Richardson 75080,USA
4. School of Medical Sciences,Tsinghua University,Beijing 100084,China
5. UTS-SUStech Joint Research Centre for Biomedical Materials & Devices,Department of Biomedical Engineering,College of Engineering,Southern University of Science and Technology,Shenzhen,Guangdong,China
6. Institute for Biomedical Materials and Devices (IBMD),Faculty of Science,University of Technology Sydney,Sydney,NSW 2007,Australia
7. National Biomedical Imaging Center,Peking University,Beijing 100871,China
8. Center for Synthetic & Systems Biology
9. Department of Automation,Tsinghua University,Beijing 100084,China
折叠

摘要

引用本文复制引用

Meiling Guan,Zhenli Jing,Micheal Q.Zhang,Dayong Jin,Peng Xi,Juntao Gao,Miaoyan Wang,Karl Zhanghao,Xu Zhang,Meiqi Li,Wenhui Liu,Jing Niu,Xusan Yang,Long Chen..Polarization modulation with optical lock-in detection reveals universal fluorescence anisotropy of subcellular structures in live cells[J].光：科学与应用（英文版）,2022,11(1):50-62,13.

基金项目

This work was supported in part by the National Natural Science Foundation of China (81890991,61705252,62025501,61729501,31971376),the State Key Research Development Program of China (2021YFE0201100,2017YFA0505503,2017YFC0110202),the Beijing Natural Science Foundation (JQ18019),CAS Interdisciplinary innovation Team (JCTD-2020-04),Beijing Municipal Natural Science Foundation (Z200021) and Shenzhen Science and Technology Program (KQTD20170810110913065). （81890991,61705252,62025501,61729501,31971376）

光：科学与应用（英文版）

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ISSN：2095-5545

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