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Time-course monitoring of in vitro biotransformation reaction via solid-phase microextraction-ambient mass spectrometry approaches

Karol Jaroch Janusz Pawliszyn

药物分析学报：英文版2022，Vol.12Issue(1)：P.186-191,6.

药物分析学报：英文版2022，Vol.12Issue(1)：P.186-191,6.DOI:10.1016/j.jpha.2021.08.001

Time-course monitoring of in vitro biotransformation reaction via solid-phase microextraction-ambient mass spectrometry approaches

Karol Jaroch ¹Janusz Pawliszyn²

作者信息

1. Department of Chemistry,University of Waterloo,Waterloo,N2L 3G1,Canada Department of Pharmacodynamics and Molecular Pharmacology,Faculty of Pharmacy,Collegium Medicum in Bydgoszcz,Nicolaus Copernicus University in Toruń Poland,85090,Bydgoszcz,Poland
2. Department of Chemistry,University of Waterloo,Waterloo,N2L 3G1,Canada
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摘要

关键词

Solid-phase microextraction/Coated probe electrospray ionization/Coated blade spray/Combretastatin/Biotransformation/Prodrug activation

分类

医药卫生

引用本文复制引用

Karol Jaroch,Janusz Pawliszyn..Time-course monitoring of in vitro biotransformation reaction via solid-phase microextraction-ambient mass spectrometry approaches[J].药物分析学报：英文版,2022,12(1):P.186-191,6.

基金项目

supported by Shimadzu Scientific Instruments(Columbia,MD,USA)and Canada’s National Science and Engineering Research Council-Industrial Research Chair(NSERC-IRC)program,grant number IRCPJ 184412-15 （Columbia,MD,USA）

药物分析学报：英文版

OACSCDSCI

ISSN：2095-1779

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