分析测试学报2022，Vol.41Issue(4)：454-466,13.DOI:10.19969/j.fxcsxb.21122001
半花菁染料用于分子影像的研究进展
Research Progress of Hemicyanine Dye for Molecular Imaging
摘要
Abstract
Molecular imaging has been widely applied to the research of fundamental biological processes,diagnosis, treatment design and therapeutic outcome assessment on many diseases.Hemicyanine(HCy)dye is a suitable bioim?aging agent due to its good photophysical properties, biocompatibility and low toxicity to living systems. A huge amount of research work involving probes based on the HCy dye for molecular imaging has emerged in recent years . This review focuses on the development of probes based on HCy dye for fluorescence and multimodal imaging in a sys?tematic manner. Design strategies of the activatable HCy probes and their successful applications as bioimaging agents are described in detail. In addition,the future development of HCy probes for molecular imaging is discussed .关键词
半花菁染料/分子影像/荧光成像/多模态成像Key words
hemicyanine/molecular imaging/fluorescence imaging/multimodal imaging分类
化学化工引用本文复制引用
吴方铮,张乐乐,海子娟..半花菁染料用于分子影像的研究进展[J].分析测试学报,2022,41(4):454-466,13.基金项目
Foundation item:the National Natural Science Foundation of China(21904002) （21904002）
the Natural Science Foundation of Anhui Province(2008085QB94) （2008085QB94）
