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Genetically encoded BRET-activated photodynamic therapy for the treatment of deep-seated tumors

Elena I.Shramova Stepan P.Chumakov Victoria O.Shipunova Anastasiya V.Ryabova Georgij B.Telegin Andrei V.Kabashin Sergey M.Deyev Galina M.Proshkina

光：科学与应用（英文版）2022，Vol.11Issue(3)：311-323,13.

Genetically encoded BRET-activated photodynamic therapy for the treatment of deep-seated tumors

Elena I.Shramova ¹Stepan P.Chumakov ¹Victoria O.Shipunova ¹Anastasiya V.Ryabova ²Georgij B.Telegin ³Andrei V.Kabashin ⁴Sergey M.Deyev ²Galina M.Proshkina⁵

作者信息

1. Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry,Russian Academy of Sciences,16/10 Miklukho-Maklaya Street,Moscow 117997,Russia
2. MEPhI(Moscow Engineering Physics Institute),Institute of Engineering Physics for Biomedicine(PhysBio),31 Kashirskoe shosse,Moscow 115409,Russia
3. Prokhorov General Physics Institute,Russian Academy of Sciences,Vavilova,38,Moscow 119991,Russia
4. Branch of Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry,Russian Academy of Sciences,Prospect Nauki 6,Pushchino 142290,Russia
5. Aix Marseille University,CNRS,LP3,163 Ave.De Luminy,Case 917,13288 Marseille,France
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摘要

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Elena I.Shramova,Stepan P.Chumakov,Victoria O.Shipunova,Anastasiya V.Ryabova,Georgij B.Telegin,Andrei V.Kabashin,Sergey M.Deyev,Galina M.Proshkina..Genetically encoded BRET-activated photodynamic therapy for the treatment of deep-seated tumors[J].光：科学与应用（英文版）,2022,11(3):311-323,13.

基金项目

The authors acknowledge the project No.18-29-09023(in part of genetic construction and stable cell lines expressing NanoLuc and NanoLuc-miniSOG gene production)provided by Russian Foundation for Basic Research,the project No.21-74-30016"Organotypic tumor models using microfluidic technologies"(in part of experiments on animals)provided by Russian Science Foundation,grant No.19-54-06001(in part of in vitro experiments)provided by Russian Foundation for Basic Research and Ministry of Science and Technology of Israel(grant No.3-16495).The fluorescent confocal microscopic images obtained using the equipment of the Center for Collective Use of Scientific Equipment No.74834"Technological and diagnostic center for the production,research and certification of micro and nanostructures"in GPI RAS. （in part of genetic construction and stable cell lines expressing NanoLuc and NanoLuc-miniSOG gene production）

光：科学与应用（英文版）

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ISSN：2095-5545

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