中国医药科学2022，Vol.12Issue(9)：169-172,191,5.
血清肠脂肪酸结合蛋白联合多层螺旋CTA诊断急性缺血性肠病价值的研究
Study on the value of serum intestinal fatty acid binding protein combined with multi-layer spiral CTA in the diagnosis of acute ischemic bowel disease
摘要
Abstract
Objective By comparing the imaging characteristics of serum intestinal fatty acid binding protein (I-FABP) and multi-slice spiral CT angiography (MSCTA) in patients with acute ischemic bowel disease and non-acute ischemic bowel disease, the correlation between the two was analyzed and the diagnostic efficacy of the two was compared. Methods A total of 65 patients with acute abdominal pain in the First People’s Hospital of Nanning from March 2015 to December 2020 were selected. Among them, 30 patients with acute ischemic bowel disease were in the observation group, and the other 35 patients with non-acute ischemic bowel disease were in the control group. Compare the diagnostic efficacy of serum I-FABP and MSCTA scores for acute ischemic bowel disease, explore the combined diagnostic efficacy of the two, and analyze their prognostic predictive ability for acute ischemic bowel disease. Results The serum I-FABP level and MSCTA score of the observation group were higher than those of the control group, and this differences were statistically significant (P < 0.05); both serum I-FABP level and MSCTA score had an impact on the diagnosis of acute ischemic bowel disease, and this differences were statistically significant (P < 0.05).The cut-off value of serum I-FABP level for the diagnosis of acute ischemic bowel disease was 125.65μg/L, the cut-off value of MSCTA score for the diagnosis of acute ischemic bowel disease was 2.5 points. The serum I-FABP level, MSCTA score, and combined detection of the area under the ROC curve for the diagnosis of acute ischemic bowel disease were 0.880, 0.761, and 0.885, respectively. The combined detection of acute ischemic bowel disease was higher than the MSCTA score diagnosis efficiency, the difference have statistical significance (P <0.05). Conclusion The detection of serum I-FABP combined with MSCTA can help to improve the diagnostic efficiency of acute ischemic bowel disease.关键词
肠脂肪酸结合蛋白/多层螺旋CT血管造影/急性缺血性肠病/诊断Key words
Intestinal fatty acid binding protein/Multi-slice spiral CT angiography/Acute ischemic bowel disease/Diagnosis分类
医药卫生引用本文复制引用
张伟伟,黄炎东,王家旭,唐少波..血清肠脂肪酸结合蛋白联合多层螺旋CTA诊断急性缺血性肠病价值的研究[J].中国医药科学,2022,12(9):169-172,191,5.基金项目
广西壮族自治区卫生健康委员会自筹经费科研课题(Z2015277). （Z2015277）
