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Development of a novel multi-functional integrated bioconjugate effectively targeting K-Ras mutant pancreatic cancer

Yang-Yang Wang Liang Li Xiu-Jun Liu Qing-Fang Miao Yi Li Meng-Ran Zhang Yong-Su Zhen

药物分析学报（英文）2022，Vol.12Issue(2)：232-242,11.

Development of a novel multi-functional integrated bioconjugate effectively targeting K-Ras mutant pancreatic cancer

Yang-Yang Wang ¹Liang Li ²Xiu-Jun Liu ²Qing-Fang Miao ²Yi Li ²Meng-Ran Zhang ²Yong-Su Zhen²

作者信息

1. Department of Pediatric Oncology,Tianjin Medical University Cancer Institute and Hospital,Tianjin,300060,China
2. NHC Key Laboratory of Biotechnology of Antibiotics,Department of Oncology,Institute of Medicinal Biotechnology,Chinese Academy of Medical Sciences&Peking Union Medical College,Beijing,100050,China
折叠

摘要

关键词

Pancreatic cancer/Folate receptor/Multi-functional/Macropinocytosis-enhanced/Bioconjugate/K-Ras/PEGylation

Key words

Pancreatic cancer/Folate receptor/Multi-functional/Macropinocytosis-enhanced/Bioconjugate/K-Ras/PEGylation

引用本文复制引用

Yang-Yang Wang,Liang Li,Xiu-Jun Liu,Qing-Fang Miao,Yi Li,Meng-Ran Zhang,Yong-Su Zhen..Development of a novel multi-functional integrated bioconjugate effectively targeting K-Ras mutant pancreatic cancer[J].药物分析学报（英文）,2022,12(2):232-242,11.

基金项目

This work was supported by grants from CAMS Innovation Fund for Medical Sciences(Grant No.:2021-I2M-1-026),Scientific Research Project of Tianjin Education Commission(Grant No.:2020KJ140),and Tianjin Health Research Project(Grant No.:KJ20017).The authors are grateful for all the participants in this study. （Grant No.:2021-I2M-1-026）

药物分析学报（英文）

OACSCDSCI

ISSN：2095-1779

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