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Restoring the dampened expression of the core clock molecule BMAL1 protects against compression-induced intervertebral disc degeneration

Dong Wang Bo Gao Chao Zheng Jianxin Mao Chu Gao Xin He Pengzhen Cheng Huanbo Wang Jianmin Zheng Judith A.Hoyland Qing-Jun Meng Pandi Peng Zhuojing Luo Liu Yang Michal Dudek Xueyu Hu Xiaolong Xu Qiliang Shang Di Wang Haoruo Jia Han Wang

骨研究（英文版）2022，Vol.10Issue(2)：297-309,13.

Restoring the dampened expression of the core clock molecule BMAL1 protects against compression-induced intervertebral disc degeneration

Dong Wang ¹Bo Gao ¹Chao Zheng ¹Jianxin Mao ¹Chu Gao ¹Xin He ²Pengzhen Cheng ¹Huanbo Wang ¹Jianmin Zheng ³Judith A.Hoyland ⁴Qing-Jun Meng ⁴Pandi Peng ⁵Zhuojing Luo ¹Liu Yang ⁶Michal Dudek ¹Xueyu Hu ⁶Xiaolong Xu ¹Qiliang Shang ⁶Di Wang ⁴Haoruo Jia ⁵Han Wang¹

作者信息

1. Institute of Orthopedic Surgery,Xijing Hospital,Fourth Military Medical University,Xi'an 710032,People's Republic of China
2. Department of Medicine Chemistry and Pharmaceutical Analysis,School of Pharmacy,Fourth Military Medical University,Xi'an 710032,People's Republic of China
3. Radiology Department,Xijing Hospital,Fourth Military Medical University,Xi'an 710032,People's Republic of China
4. School of Biological Sciences,Faculty of Biology,Medicine and Health,University of Manchester,Manchester M13 9PL,UK
5. Wellcome Centre for Cell Matrix Research,University of Manchester,Manchester M13 9PL,UK
6. Medical Research Institute,Northwestern Polytechnical University,Xi'an 710068,People's Republic of China
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摘要

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Dong Wang,Bo Gao,Chao Zheng,Jianxin Mao,Chu Gao,Xin He,Pengzhen Cheng,Huanbo Wang,Jianmin Zheng,Judith A.Hoyland,Qing-Jun Meng,Pandi Peng,Zhuojing Luo,Liu Yang,Michal Dudek,Xueyu Hu,Xiaolong Xu,Qiliang Shang,Di Wang,Haoruo Jia,Han Wang..Restoring the dampened expression of the core clock molecule BMAL1 protects against compression-induced intervertebral disc degeneration[J].骨研究（英文版）,2022,10(2):297-309,13.

基金项目

This work was supported by the National Natural Science Foundation of China(82020108019,82130070,81730065,82002347,81972032,and 81902202),The Medical Research Council(UK)MR/T016744/1 and MR/P010709/1 and the Versus Arthritis Senior Research Fellowship Award 20875. （82020108019,82130070,81730065,82002347,81972032,and 81902202）

骨研究（英文版）

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ISSN：2095-4700

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